Research progress of glycyrrhizin in the treatment of osteoarthritis
Kouqiang hemian waike zazhiGlycyrrhizin is extracted from licorice root and has anti-inflammatory, antioxidant, anti-tumor, anti-viral and other effects. At present, there are few studies on the role and mechanism of glycyrrhizin in osteoarthritis.
HU Zhihui, LONG Xing
doaj +2 more sources
Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on post-contrast acute kidney injury [PDF]
Scientific Reports, 2021 Post contrast-acute kidney injury (PC-AKI) is defined as the deterioration of renal function after administration of iodinated contrast media. HMGB1 is known to play an important role in the development of acute kidney injury.
Hyewon Oh +5 more
doaj +2 more sources
Glycyrrhizin Suppresses the Growth of Human NSCLC Cell Line HCC827 by Downregulating HMGB1 Level [PDF]
, 2018 Lung cancer has very high mortality and glycyrrhizin was found to significantly inhibit the growth of lung cancer cells in vitro and tissues in mice. However, the detailed inhibitory role of glycyrrhizin in the growth of lung cancer is still unclear.
Jindong Wang +14 more
core +2 more sources
Effects of Glycyrrhizin in a Mouse Model of Lung Adenocarcinoma
Cellular Physiology and Biochemistry, 2017 Background: Currently, there is a global attempt to identify potential anti-cancer agents with low toxicity. Previous studies have found that glycyrrhizin exerts anti-cancer action with low toxicity through suppressing thromboxane A2 (TxA2) in lung ...
Qing-Ping Deng +4 more
doaj +2 more sources
Glycyrrhizin and Coronaviruses
, 2020 The SARS-CoV-2 is a novel β-coronavirus, which is enveloped non-segmented positive-sense RNA virus that causes COVID-19 disease. Few studies showed that glycyrrhizin from liquorice root has some anti-viral effect on coronaviruses, what opens the question can glycyrrhizin be used as experimental drug for the treatment of COVID-19 patients or can this ...
Domina Petric
openaire +2 more sources
Effects of glycyrrhizin on the pharmacokinetics of paeoniflorin in rats and its potential mechanism
Pharmaceutical Biology, 2019 Context: Paeoniflorin is reported to possess numerous pharmacological activities. Paeoniflorin and glycyrrhizin are always used together for the treatment of disease in China clinics; however, the drug–drug interaction between glycyrrhizin and ...
Hongjuan Sun, Jingfeng Wang, Juan Lv
doaj +2 more sources
Glycyrrhizin Suppresses Lung Adenocarcinoma Cell Growth Through Inhibition of Thromboxane Synthase [PDF]
Cellular Physiology and Biochemistry, 2014 Background/Aims: The effects of glycyrrhizin treatment in lung cancer remain undetermined, despite extensive studies of the anti-tumor activities of glycyrrhizin. Methods: Lung adenocarcinoma A549 and NCI-H23 cell lines were used in this study.
Run-Yue Huang +5 more
doaj +2 more sources
EST analysis reveals putative genes involved in glycyrrhizin biosynthesis [PDF]
BMC Genomics, 2010 Background Glycyrrhiza uralensis is one of the most popular medicinal plants in the world and is also widely used in the flavoring of food and tobacco.
Wang Ning +9 more
doaj +2 more sources
Bioavailability Study of Glycyrrhetic Acid after Oral Administration of Glycyrrhizin in Rats; Relevance to the Intestinal Bacterial Hydrolysis [PDF]
, 1996 To clarify the metabolic fate of glycyrrhizin when orally ingested, we investigated the bioavailability of glycyrrhetic acid, the aglycone of glycyrrhizin, after intravenous or oral administration of glycyrrhetic acid (5.7 mg kg−1, equimolar to ...
Masao Maruno +6 more
core +2 more sources
Glycyrrhizin attenuates endotoxin- induced acute liver injury after partial hepatectomy in rats
Brazilian Journal of Medical and Biological Research, 2007 Massive hepatectomy associated with infection induces liver dysfunction, or even multiple organ failure and death. Glycyrrhizin has been shown to exhibit anti-oxidant and anti-inflammatory activities.
B. Tang, H. Qiao, F. Meng, X. Sun
doaj +1 more source