Results 11 to 20 of about 14,486 (271)

Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on post-contrast acute kidney injury [PDF]

Scientific Reports, 2021
Post contrast-acute kidney injury (PC-AKI) is defined as the deterioration of renal function after administration of iodinated contrast media. HMGB1 is known to play an important role in the development of acute kidney injury.
Hyewon Oh, Arom Choi, Nieun Seo, Joon Seok Lim, Je Sung You, Yong Eun Chung   +5 more
doaj   +2 more sources

Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects [PDF]

Frontiers in Pharmacology
BackgroundFor patients with epilepsy, antiseizure medication remains the primary treatment; however, it is ineffective in approximately 30% of cases. These patients experience progressive neuronal damage and poor outcomes.
Lei Wei, Sijie Ou, Youshi Meng, Lanfeng Sun, Lin Zhang, Yuling Lu, Yuan Wu   +6 more
doaj   +2 more sources

Dietary glycyrrhizin enhances reproductive performance by improving intestinal microbiota, liver lipid metabolism and ovarian senescence in aged breeder hens. [PDF]

J Anim Sci Biotechnol
Huang Z, Liu H, Wang G, Ge H, Shi Y, Feng J, Li C, Zhang M.   +7 more
europepmc   +3 more sources

Therapeutic potential of glycyrrhizin in nervous system diseases. [PDF]

Chin Med J (Engl)
An J, Han M, Chen P, Wang L, Gao L, Zhou Z, Huang S, Du J, Peng F.   +8 more
europepmc   +2 more sources

Protective effect of glycyrrhizin on coronary microembolization‐induced myocardial dysfunction in rats

Pharmacology Research & Perspectives, 2021
Coronary microembolization (CME)‐induced inflammation and cardiomyocyte apoptosis are two key factors contributing to CME‐induced myocardial dysfunction.
Yonggang Yuan, Bing Li, Wanzhong Peng, Zesheng Xu   +3 more
doaj   +1 more source

Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia [PDF]

, 2020
Background: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer-associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy
Chiappalupi, S., Coletti, D., Donato, R., Renga, G., Riuzzi, F., Romani, L., Sagheddu, R., Salvadori, L., Sorci, G., Vukasinovic, A.   +9 more
core   +1 more source

Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis

BMC Immunology, 2021
Background The anti-inflammatory effect of glycyrrhizin has been widely recognized, while the specific mechanism of glycyrrhizin in psoriasis remains poorly understood.
Huang Qiong, Ling Han, Nanxue Zhang, Huyan Chen, Kexiang Yan, Zhenghua Zhang, Ying Ma, Jinhua Xu   +7 more
doaj   +1 more source

Role of High-Mobility Group Box-1 in Liver Pathogenesis [PDF]

, 2019
High-mobility group box 1 (HMGB1) is a highly abundant DNA-binding protein that can relocate to the cytosol or undergo extracellular release during cellular stress or death. HMGB1 has a functional versatility depending on its cellular location.
Huda, Nazmul, Khambu, Bilon, Yan, Shengmin, Yin, Xiao-Ming   +3 more
core   +1 more source

Investigating the efficacy of dipotassium glycyrrhizin emollients in adult atopic dermatitis: A focused randomized parallel-controlled clinical study. [PDF]

Pak J Med Sci
Xia J, Liu X, Wang Z, Zhang Y, Jiang G.
europepmc   +2 more sources

Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]

, 2015
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu, Oga, Enoche Florence, Sekine, Shuichi, Shitara, Yoshihisa   +3 more
core   +1 more source