Results 91 to 100 of about 187,715 (167)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Genomic analysis of Inonotus hispidus provides insights into its medicinal properties and evolutionary dynamics. [PDF]

Sci Rep
Ding D, Wang H, Liang J, Su C, Zhang M, Jiao F, Bao L, Wang X.   +7 more
europepmc   +1 more source

Physicochemical, Nutritional, and Medicinal Properties of Opuntia ficus-indica (L.) Mill. and Its Main Agro-Industrial Use: A Review. [PDF]

Plants (Basel), 2023
Martins M, Ribeiro MH, Almeida CMM.
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Habitat-elevation and plant organ-type affect the phytochemical contents and the medicinal properties of Senna italica in the arid climate of Fujairah. [PDF]

Sci Rep
Tsombou FM, Ridouane FL, Alhmoudi AMSA, Alhmoudi MASM, Pakam S, Al Dhanhani ASS.   +5 more
europepmc   +1 more source

Exploring native Scutellaria species provides insight into differential accumulation of flavones with medicinal properties. [PDF]

Sci Rep, 2022
Costine B, Zhang M, Chhajed S, Pearson B, Chen S, Nadakuduti SS.   +5 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

The Pharmacological Potential of <i>Marantodes pumilum</i>: A Comprehensive Review of Its Medicinal Properties. [PDF]

Int J Mol Sci
Adam SH, Junaidi NSSA, Halim S, Ramli NF, Mokhtar MH.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Biological and Medicinal Properties of <i>Chrysanthemum boreale</i> Makino and Its Bioactive Products. [PDF]

Int J Mol Sci
Bailly C.
europepmc   +1 more source