Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Integrative analyses of the transcriptome and metabolome of Huzhang (Pinellia pedatisecta Schott) uncover the molecular genetic basis of its medicinal properties. [PDF]
Pan C, Chen J, Qian Z.
europepmc +1 more source
Plant ingredients in Thai food: a well-rounded diet for natural bioactive associated with medicinal properties. [PDF]
Buathong R, Duangsrisai S.
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
A comprehensive review of the medicinal properties of <i>Terminalia arjuna</i> and its major constituent arjunolic acid: a natural product source for new drug leads. [PDF]
Bhujel M +3 more
europepmc +1 more source
Diversity of Citrullus colocynthis (L.) Schrad Seeds Extracts: Detailed Chemical Profiling and Evaluation of Their Medicinal Properties. [PDF]
Khan M +5 more
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
<i>Adiantum capillus-veneris:</i> A Comprehensive Review of Its Medicinal Properties, Bioactive Compounds, and Advanced Extraction Techniques. [PDF]
Qadir SA +8 more
europepmc +1 more source
Some Natural Photosensitizers and Their Medicinal Properties for Use in Photodynamic Therapy. [PDF]
Kubrak TP +5 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source

