Results 101 to 110 of about 76,525,237 (343)

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Human Factors and Simulation in Emergency Medicine [PDF]

, 2017
This consensus group from the 2017 Academic Emergency Medicine Consensus Conference Catalyzing System Change through Health Care Simulation: Systems, Competency, and Outcomes held in Orlando, Florida, on May 16, 2017, focused on the use of human ...
Dylan D. Cooper, Perry, Kimberly, Lei, Charles, Lewandowski, William E., +1 additional author, William E. Lewandowski, Margaret K. Sande, Cooper, Dylan D., Sande, M. K., Ambrose H. Wong, Hayden, E. M., Michael Cassara, Emily M. Hayden, Leo Kobayashi, Lei, C., Wong, Ambrose H., Cassara, Michael, Cassara, M., Sande, Margaret K., Ackerman, J., Scerbo, M. W., Kobayashi, L., Kimberly Perry, Scerbo, Mark W., Cooper, D. D., Kobayashi, Leo, Charles Lei, Hayden, Emily M., Ackerman, Jeremy, Jeremy Ackerman, Wong, A. H., Perry, K., Mark W. Scerbo   +32 more
core   +1 more source

I’ve Gut A Feeling: Microbiota Impacting the Conceptual and Experimental Perspectives of Personalized Medicine

International Journal of Molecular Sciences, 2018
In recent years, the human microbiota has gained increasing relevance both in research and clinical fields. Increasing studies seem to suggest the centrality of the microbiota and its composition both in the development and maintenance of what we call ...
A. Amedei, F. Boem
semanticscholar   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Democratising the design and delivery of large-scale randomised, controlled clinical trials in primary care: A personal view

European Journal of General Practice
Background Rapid identification of effective treatments for use in the community during a pandemic is vital for the well-being of individuals and the sustainability of healthcare systems and society.
Christopher C. Butler
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Experimental medicine

, 1949
EXPERIMENTAL MEDICINE Experimental medicine (-
Bernard, Claude
core   +3 more sources

Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency

Nature Communications, 2020
Metastatic dissemination in breast cancer patients occurs early in malignant transformation, raising questions about how disseminated cancer cells (DCC) progress at distant sites.
Melanie Werner-Klein, Ana Grujovic, Christoph Irlbeck, Milan Obradović, Martin Hoffmann, Huiqin Koerkel-Qu, Xin Lu, Steffi Treitschke, Cäcilia Köstler, Catherine Botteron, Kathrin Weidele, Christian Werno, Bernhard Polzer, Stefan Kirsch, Miodrag Gužvić, Jens Warfsmann, Kamran Honarnejad, Zbigniew Czyz, Giancarlo Feliciello, Isabell Blochberger, Sandra Grunewald, Elisabeth Schneider, Gundula Haunschild, Nina Patwary, Severin Guetter, Sandra Huber, Brigitte Rack, Nadia Harbeck, Stefan Buchholz, Petra Rümmele, Norbert Heine, Stefan Rose-John, Christoph A. Klein   +32 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Bridging genomics research between developed and developing countries: The Genomic Medicine Alliance [PDF]

, 2014
The Genomic Medicine Alliance is a global academic research network that aims to establish and strengthen collaborative ties between the various genomic medicine stakeholders.
Williams, Marc S, Innocenti, Federico, Brand, Angela, Dolzan, Vita, Prainsack, Barbara, Williams, Marc S., Patrinos, George P., Lee, Ming Ta Michael, Vayena, Effy, Fortina, Paolo, Cooper, David Neil, Innocenti, Federica, Michael Lee, Ming Ta, Vozikis, Athanassios, Cooper, David N., MacEk, Milan, Al-Mulla, Fahd, Cooper, David, Lee MTM, Michael Lee MT, Williams MS, SQUASSINA, ALESSIO, Fortina P, Dolzan V, Macek M. Jr, Cooper DN, Innocenti F, Prainsack B, Al-Mulla F, Squassina A, Al Mulla F, Brand A, Macek M, Vayena E, Vozikis A, Patrinos GP   +35 more
core   +1 more source