Results 111 to 120 of about 76,525,237 (343)

Could Trivalent LAIV Protect Against Both Genetic Lineages of Influenza B Virus?

Vaccine Research, 2019
Introduction: The global co-circulation of two influenza B virus genetic lineages known as B/Yamagata and B/Victoria may lead to a mismatch between the circulating virus and the strain recommended for use in influenza vaccines.
Irina Kiseleva, Ekaterina Stepanova, Elena Krutikova, Svetlana Donina, Andrey Rekstin, Ekaterina Bazhenova, Maria Pisareva, Anastasia Katelnikova, Kirill Kryshen, Arman Muzhikyan, Elena Grigorieva, Larisa Rudenko   +11 more
doaj  

Repeated behavioral testing and the use of summary measures reveal trait anxiety in preclinical rodent models

Translational Psychiatry
The reliability and validity of preclinical anxiety testing is essential for translating animal research into clinical use. However, the commonly used anxiety tests lack inter-test correlations and face challenges with repeatability.
Zoltán K. Varga, Diána Pejtsik, Máté Tóth, Zoltán Balogh, Manó Aliczki, László Szente, Gyula Y. Balla, Levente Kontra, Zsófia Eckert, Huba Szebik, Zsolt Borhegyi, Éva Mikics   +11 more
doaj   +1 more source

Connective tissue and the problems of its pathological conditions

Бюллетень сибирской медицины, 2018
This review and discussion article focuses on the physiology and pathology of connective tissue system and its interaction with mononuclear phagocyte system (MPS) in initiation and development of fibrosis.
V. A. Shkurupy, L. B. Kim, A. V. Kovner, L. A. Cherdantseva   +3 more
doaj   +1 more source

Drosophila melanogaster in nutrition research—the importance of standardizing experimental diets

Genes & Nutrition, 2019
The fruit fly Drosophila melanogaster has been increasingly recognized as an important model organism in nutrition research. In order to conduct nutritional studies in fruit flies, special attention should be given to the composition of the experimental ...
K. Lüersen, T. Röder, G. Rimbach
semanticscholar   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential

npj Digital Medicine
AI-driven virtual cell models show the potential to transform the paradigm of life sciences research by integrating multimodal omics data (e.g., single-cell transcriptomics and proteomics) with advanced algorithms such as deep generative models and graph
Chun-Yu Ma, Han Zhang, Yiwei Rao, Xin-Yu Jiang, Bo-Heng Liu, Zhi-Kang Sun, Zhenyu Song, Yuan Gao, Yuhao Cui, Xin-Yu Liu, Zedong Li   +10 more
semanticscholar   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Chinese medicine in Australia [PDF]

, 2016
Objectives: Chinese medicine is a complex domain of theoretical and practical approaches that is being increasingly put under the research spotlight.
Moore, A, Bensoussan, Alan (R7273), Komesaroff, PA, Komesaroff, Paul A., Alan Bensoussan, Xu, Hong, O'Brien, Kylie A. (R14413), Kylie O'Brien, Amber Moore, O'Brien, K, Bensoussan, Alan, Hong Xu, Bensoussan, A, Moore, Amber, O'brien, Kylie, Paul A. Komesaroff   +15 more
core   +1 more source

The relationship between non-HDL cholesterol and macrophage phenotypes in human adipose tissue

Journal of Lipid Research, 2016
Data from experimental animal models and in vitro studies suggest that both hyperlipoproteinemia and obesity predispose to development of proinflammatory pathways of macrophages within adipose tissue.
Rudolf Poledne, Ivana Kralova Lesna, Anna Kralova, Jiri Fronek, Sona Cejkova   +4 more
doaj   +1 more source

The scientific basis of synergy in traditional Chinese medicine: physicochemical, pharmacokinetic, and pharmacodynamic perspectives

Chinese Medicine
Traditional Chinese medicine, with millennia of history, demonstrates significant therapeutic efficacy against diverse diseases. A key characteristic of traditional Chinese medicine lies in the use of compound formulas—multi-herb concoctions that enhance
Xi Wang, Xiaoying Shi, Zhe-Xing Xi, Zhitong Zhang, Zichen Luo, Jin Wang, Jinjun Shan   +6 more
semanticscholar   +1 more source