Results 51 to 60 of about 6,160,858 (313)

TCM-GPT: Efficient Pre-training of Large Language Models for Domain Adaptation in Traditional Chinese Medicine [PDF]

arXiv, 2023
Pre-training and fine-tuning have emerged as a promising paradigm across various natural language processing (NLP) tasks. The effectiveness of pretrained large language models (LLM) has witnessed further enhancement, holding potential for applications in the field of medicine, particularly in the context of Traditional Chinese Medicine (TCM).
arxiv  

Improved Traditional Medicines in Mali [PDF]

The Journal of Alternative and Complementary Medicine, 2012
Mali is unusual in enjoying a high level of government support for research and development of traditional medicines. The Department for Traditional Medicine, within the National Institute for Research on Public Health (part of the Ministry of Health), was founded in 1968 (originally as the National Institute of Phytotherapy and Traditional Medicine ...
Willcox, Merlin, Sanogo, Rokia, Diakite, Chiaka, Giani, Sergio, Paulsen, Berit Smestad, Diallo, Drissa   +5 more
openaire   +6 more sources

Network medicine framework reveals generic herb-symptom effectiveness of Traditional Chinese Medicine [PDF]

arXiv, 2022
Traditional Chinese medicine (TCM) relies on natural medical products to treat symptoms and diseases. While clinical data have demonstrated the effectiveness of selected TCM-based treatments, the mechanistic root of how TCM herbs treat diseases remains largely unknown. More importantly, current approaches focus on single herbs or prescriptions, missing
arxiv  

ETCM: an encyclopaedia of traditional Chinese medicine

Nucleic Acids Res., 2018
Traditional Chinese medicine (TCM) is not only an effective solution for primary health care, but also a great resource for drug innovation and discovery.
Haiyu Xu, Yan-Qiong Zhang, Zhenming Liu, Tong Chen, C. Lv, Shihuan Tang, Xiao-Bo Zhang, Wei Zhang, Zhi-Yong Li, R. Zhou, Hong-Jun Yang, Xiu-Jie Wang, Luqi Huang   +12 more
semanticscholar   +1 more source

Streptomyces from traditional medicine: sources of new innovations in antibiotic discovery

Journal of Medical Microbiology, 2020
Given the increased reporting of multi-resistant bacteria and the shortage of newly approved medicines, researchers have been looking towards extreme and unusual environments as a new source of antibiotics.
Gerry A. Quinn, Aiya M. Banat, Alyaa M. Abdelhameed, I. Banat   +3 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Isovaleramida, principio anticonvulsivo aislado de Valeriana pavonii

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. El fraccionamiento fitoquímico de Valeriana pavonii, especie vegetal nativa utilizada tradicionalmente en Colombia con fines tranquilizantes, condujo al aislamiento e identificación de la isovaleramida, uno de los principios responsables de
Sara Emilia Giraldo, Javier Rincón, Pilar Puebla, Mariel Marder, Cristina Wasowski, Nadezdha Vergel, Mario Francisco Guerrero   +6 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Traditional Chinese medicine for epilepsy [PDF]

Cochrane Database of Systematic Reviews, 2007
Seizures are poorly controlled in many people with epilepsy, despite current antiepileptic treatments. Some turn to alternative or complementary therapy to treat their condition and the use of traditional Chinese medicinal herbs (TCMH) is increasingly popular.
Li He, Xiaoyan Chen, Dong Zhou, Qifu Li
openaire   +3 more sources