Results 111 to 120 of about 19,462,706 (409)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Radiation exposure from diagnostic nuclear medicine examinations in golestan province [PDF]

, 2013
Introduction: The aim of present study was to estimate effective dose from most common procedures performed in nuclear medicine departments of Golestan province.
Asli, I.N., Assadi, M., Javadi, H., Mogharrabi, M., Parach, A.A., Pashazadeh, A.M., Tabei, F.   +6 more
core  

Aerosols in Medicine and Veterinary Medicine [PDF]

Pneumologie, 2003
P, Reinhold, H, Fehrenbach
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine

, 2018
Marc D. Ruben, Gang Wu, David F. Smith, Robert E. Schmidt, Lauren J. Francey, Yin Yeng Lee, Ron C. Anafi, John B. Hogenesch   +7 more
openalex   +2 more sources

A new initiative on precision medicine.

New England Journal of Medicine, 2015
Francis S. Collins, Harold Varmus
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Macrophage-based therapeutic strategies in regenerative medicine

, 2017
Kara L. Spiller, Timothy J. Koh
openalex   +2 more sources

Research progress on the ethanol precipitation process of traditional Chinese medicine [PDF]

, 2020
Yanni Tai, Ji-Chen Shen, Yu Luo, Haibin Qu, Xingchu Gong   +4 more
openalex   +1 more source

Retracted: Analysis of the Effectiveness of Transradial Access Puncture in the Application of Complications and Comfort after Cerebral Angiography

Emergency Medicine International, 2023
Emergency Medicine International
doaj   +1 more source