Results 31 to 40 of about 17,401,288 (421)
Human organoids: model systems for human biology and medicine
Nature reviews. Molecular cell biology, 2020 The historical reliance of biological research on the use of animal models has sometimes made it challenging to address questions that are specific to the understanding of human biology and disease. But with the advent of human organoids — which are stem
Jihoon Kim, B. Koo, J. Knoblich
semanticscholar +1 more source
Population Ecology, EarlyView.In this article, we tested optimal SNP filtering strategies for accurate parentage assignment and pedigree reconstruction for a wild population of red‐spotted masu salmon, Oncorhynchus masou ishikawae. We found that mid‐point filtering in terms of call rate and minor allele frequency performs well for pedigree reconstruction.
Shohei Noda +6 more
wiley +1 more source
PLOS medicine at 10 years: two imperatives. [PDF]
PLoS Medicine, 2014 On the occasion of the journal's tenth anniversary, the PLOS Medicine Editors reflect on the challenge of attaining universal availability for high-quality medical research. Please see later in the article for the Editors' Summary.
PLOS Medicine Editors
doaj +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Medicinal Boxes Recognition on a Deep Transfer Learning Augmented Reality Mobile Application [PDF]
arXiv, 2022 Taking medicines is a fundamental aspect to cure illnesses. However, studies have shown that it can be hard for patients to remember the correct posology. More aggravating, a wrong dosage generally causes the disease to worsen. Although, all relevant instructions for a medicine are summarized in the corresponding patient information leaflet, the latter
arxiv
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Ethics for Digital Medicine: A Path for Ethical Emerging Medical IoT Design [PDF]
arXiv, 2022 The dawn of the digital medicine era, ushered in by increasingly powerful embedded systems and Internet of Things (IoT) computing devices, is creating new therapies and biomedical solutions that promise to positively transform our quality of life. However, the digital medicine revolution also creates unforeseen and complex ethical, regulatory, and ...
arxiv
, 2005 Advice compiled by Boston University School of Medicine students for incoming first year students and third or fourth year students preparing for clinical ...
Boston University School of Medicine
core
The new medical model: a renewed challenge for biomedicine [PDF]
, 2017 Over the past 25 years, several new “medicines” have come screeching onto health care’s various platforms, including narrative medicine, personalized medicine, precision medicine and person-centred medicine.
Fuller, Jonathan
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source