Results 61 to 70 of about 19,462,706 (409)

Exploring Social Avoidance and Psychosocial Factors in Young Adults with Acne in East China

Clinical, Cosmetic and Investigational Dermatology
Fen Xu,1,2 Nor Aziyan Yahaya,1 Yunxian Zhou,3 Junya Chen,1 Jia Yin Ruan,4 Yue Sun,1 Mei-Chan Chong1 1Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; 2Department of Dermatology, Hangzhou Third Hospital ...
Xu F, Yahaya NA, Zhou Y, Chen J, Ruan JY, Sun Y, Chong MC   +6 more
doaj  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Contribution of traditional Chinese medicine combined with conventional western medicine treatment for the novel coronavirus disease (COVID‐19), current evidence with systematic review and meta‐analysis [PDF]

, 2021
Fei Jiang, Nana Xu, Yanxi Zhou, Jinxing Song, Jinjuan Liu, Hong Zhu, Jihong Jiang, Yonghong Xu, Rongpeng Li   +8 more
openalex   +1 more source

Causability and explainability of artificial intelligence in medicine

WIREs Data Mining Knowl. Discov., 2019
Explainable artificial intelligence (AI) is attracting much interest in medicine. Technically, the problem of explainability is as old as AI itself and classic AI represented comprehensible retraceable approaches.
Andreas Holzinger, G. Langs, H. Denk, K. Zatloukal, Heimo Müller   +4 more
semanticscholar   +1 more source

Surgical and Endovascular Management of Aortic Thrombosis in COVID-19 and Vaccine-Induced Immune Thrombotic Thrombocytopenia

Vascular Health and Risk Management
Rojan Abdollahzadeh Mirali,1 Seyedh Saba Ramazannia Toloti,2 Yasamin Bigdeli,3 Asal Ebrahimi,4 Yasamin Roointanpour,2 Meghdad Ghasemi Gorji1,2,5 1Department of Vascular Surgery, Shiraz University of Medical Sciences, Shiraz, Iran; 2Student Research ...
Abdollahzadeh Mirali R, Ramazannia Toloti SS, Bigdeli Y, Ebrahimi A, Roointanpour Y, Ghasemi Gorji M   +5 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Sustaining the Integration of Social Objectives Over Time: A Case-Based Analysis of Access to Medicine in the Pharmaceutical Industry [PDF]

, 2023
Tobias Bünder, Nikolas Rathert, Johanna Mair   +2 more
openalex   +1 more source

Assessment of Food Cravings, Food Intake, and Weight Status Among Saudi Adults in Central and Western Regions of Saudi Arabia: A Retrospective, Cross-Sectional Study

Nutrition and Dietary Supplements
Mohammed Zaid Aljulifi,1 Atheer Ayed M Alshutayli,2 Ahmed Mohammed A Kaseb,3 Faisal Mohammed Asiri,4 Renad Ibrahim Alzahrani,5 Nawaf Amer H Alharbi,5 Ghadeer Yahya Almasabi,5 Mudhawi Faisal Alsuliman,6 Mohammad Shakil Ahmad,1 Riyaz Ahmed Shaik1 ...
Aljulifi MZ, Alshutayli AAM, Kaseb AMA, Asiri FM, Alzahrani RI, Alharbi NAH, Almasabi GY, Alsuliman MF, Ahmad MS, Shaik RA   +9 more
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source