Results 161 to 170 of about 2,986,162 (251)

Acceptability and tolerability of risankizumab maintenance therapy administered via on-body injector in patients with Crohn's disease: Results of the ACCEPT-OBI study. [PDF]

Ther Adv Gastroenterol
Buisson A, Gebara K, Caron B, Boschetti G, Gilletta de Saint Joseph C, Nachury M, Brixi H, Juillerat P, Serrero M, Vuitton L, Hebuterne X, Caillo L, Blain A, Laharie D, Peyrin-Biroulet L, Altwegg R, Le Cosquer G, Pereira B, Fumery M.   +18 more
europepmc   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Stakeholder perceptions of the acceptability of an intervention to improve uptake of evidence-based emergency myocardial infarction care in Tanzania: A qualitative study. [PDF]

PLoS One
Sumner SF, Sakita FM, Haukila KF, Wanda L, Kweka GL, Mlangi JJ, Shayo P, Tarimo TG, Khanna S, Wang C, Pyne A, Manavalan P, Thielman NM, Bettger JP, Hertz JT.   +14 more
europepmc   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Enhancing attention and processing speed through home-based music rehabilitation programme after stroke in Malaysia: a feasibility randomised controlled trial protocol. [PDF]

BMJ Open
Beh WF, Wang F, Choong FC, Yap KH, Mazlan M.   +4 more
europepmc   +1 more source

Transforming Brain Organoids Into Functional Platforms: Convergence of Engineering, Imaging, AI, and Ethics

Advanced Science, EarlyView.
Brain organoids are emerging as increasingly functional human‐relevant platforms, yet limitations in vascularization, maturation, measurement, and reproducibility still constrain their translational value. This Perspective examines how microfluidics, biofabrication, advanced imaging, electrophysiology, multimodal AI, standardization, and ethical ...
Aishwarya Pantula, Kaustubh Joshi, Swarangi Samant, Greta Babakhanova, Annie Kathuria   +4 more
wiley   +1 more source

<i>From Kitchen to Clinic</i>: Study protocol for a family-centered, food-as-medicine approach using medically tailored meals and caregiver coaching in pediatric oncology care. [PDF]

Contemp Clin Trials Commun
Milliron BJ, Schlechter H, Muir C, Moss C, Henstenburg JA, Rappaport K, Boakye F, Deutsch JM, Jubelirer T.   +8 more
europepmc   +1 more source

Toward Prostate Cancer Early Warning with a Self‐Powered Wearable Biosensing Platform Integrated with Machine Learning

Advanced Science, EarlyView.
ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu, Hanxiao Chen, Qichen Yuan, Liucun Yin, Yifang Tao, Hong Wang, Yuquan Xue, Delai Fu, Huan Pang, Tie Chong, Li Xue   +10 more
wiley   +1 more source

Acceptability and Willingness to Use the "CaknaStrok" Mobile Health Application and Associated Factors Among Informal Caregivers of Post-Stroke Patients in Malaysia: Protocol for an Explanatory Sequential Mixed-Methods Study. [PDF]

Healthcare (Basel)
Bakar AFA, Aizuddin AN, Ibrahim R, Musa KI, Kamalakannan S.   +4 more
europepmc   +1 more source