Results 101 to 110 of about 5,830,342 (217)

Serious Adverse Events in Adult ICU Patients: A Substudy of the PATIENCE Cohort. [PDF]

Acta Anaesthesiol Scand
Crone V, Møller MH, Granholm A, Perner A, Alhazzani W, Al-Fares A, Hästbacka J, Ostermann M, Pfortmueller CA, Ferrer R, Blaser AR, Keus E, Szczeklik W, Krag M.   +13 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Randomized, Controlled, Crossover Trial Comparing Immediate Effects of Components of Complex Decongestive Therapy in Lower-limb Lymphedema Patients. [PDF]

Prog Rehabil Med
Oka A, Tsuji T, Abe K, Nakamura T, Kawakami M, Muraoka K, Hohri H, Sano Y, Shoji J, Kamisako M, Liu M.   +10 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Mathematics And Medicine: Does It All Add Up? [PDF]

Al Ameen Journal of Medical Sciences, 2009
Neil S Cherniack
doaj  

A Case-Based Framework for Teaching Artificial Intelligence Applications in Medical Education. [PDF]

MedEdPORTAL
Schulman RC, Razavi AS, Hardy C, Chakrapani P, Daoud AR, Mazza M, Saxena A, Grullon J, Gary PJ, Middleton F, Narsipur S.   +10 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

INTERNATIONAL EXERCISES “LIQUIDATION OF MEDICAL AND SANITARY CONSEQUENCES OF EARTHQUAKES”, YEREVAN, REPUBLIC OF ARMENIA, DECEMBER, 4-8, 2018

Медицина катастроф, 2019
Tkhokhova Z.M., Cheplyaev A.A., Byzov A.V., Kalachyov I.I.   +3 more
doaj   +1 more source

Addressing physician burnout through an accessibility lens. [PDF]

CMAJ
Norris EB, Liao P, Quon MJ.
europepmc   +1 more source