Results 111 to 120 of about 5,830,342 (217)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

When a Contaminant Is Not a Contaminant: A Case Report of Micrococcus luteus Causing Septic Shock in the Absence of Traditional Risk Factors. [PDF]

Cureus
Alajab J, Sooch MK, Yeddi M, Yeddi O, Hussein M, Yeddi A, Frimodig B.   +6 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

ORGANIZATION OF MEDICAL SUPPORT OF MASS EVENTS ON EXPERIENCE OF THE FIELD MULTIPURPOSE HOSPITAL UNIT OF ALL-RUSSIAN CENTRE FOR DISASTER MEDICINE «ZASCHITA» IN 2018

Медицина катастроф, 2018
Chubaiko V.G. , Cheplyaev A.A., Chernyak S.I., Radchenko I.V., Grabchak S.A., Bobiy B.V., Savvin Y.N., Avetisov G.M.   +7 more
doaj  

WHO Basic Emergency Care (BEC) training in Liberia: pre-course, post-course, and one-year outcomes. [PDF]

Afr J Emerg Med
Miraftab-Salo O, Ajami I, Mahteh N, Lucas A, Faulk N, Ricks-Dargba M, Freeman-Murray T, Jaung M, Bills C, Enriquez K.   +9 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

RESULTS OF SERVICE FOR DISASTER MEDICINE OF HEALTH MINISTRY OF THE RUSSIAN FEDERATION ACTIVITY IN 2017

Медицина катастроф, 2018
Chubayko V.G., Kryukov V.I., Baranova N.N., Belova A.B., Yuvakaev I.S., Radchenko I.V., Magazeyshchikova N.G.   +6 more
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Current Issues of Disaster Medicine Service According to the 2016–2017 Audit Results

Медицина катастроф, 2018
Belova A.B., Chubayko V.G., Osadchiy K.N., Yuvakaev I.S., Bobiy B.V., Sakhno I.I., Chernyak S.I.   +6 more
doaj