Results 131 to 140 of about 26,997,198 (419)
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
Integrative concept of homeostasis: translating physiology into medicine [PDF]
, 2011 To truly understand living systems they must be viewed as a whole. In order to achieve this and to come to some law to which living systems obey, data obtained on cells, tissues and organs should be integrated.
Ivan Spasojevic, Ivan Spasojevic
core +3 more sources
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018 INTRODUCTION The purpose of this systematic review is to provide supporting evidence for a clinical practice guideline on the use of actigraphy. METHODS The American Academy of Sleep Medicine commissioned a task force of experts in sleep medicine.
Michael T. Smith +6 more
semanticscholar +1 more source
The Patient-Physician Relationship: Overcoming Language and Cultural Barriers [PDF]
, 2019 The patient-physician relationship governs the field of medicine, forming the basis for all relationships, interactions, and procedures in medicine. The degree to which a patient trusts his physician and thus is willing to be receptive to medical advice ...
Lynch, Corrilynn
core +1 more source
Practical recommendations for radium-223 treatment of metastatic castration-resistant prostate cancer [PDF]
, 2017 is the first targeted alpha therapy for patients with castration resistant prostate cancer and symptomatic bone metastases. Radium-223 provides a new treatment option for this setting, but also necessitates a new treatment management approach.
Carrió, Ignasi +11 more
core +4 more sources
Personalised Medicine: Taking a New Look at the Patient [PDF]
arXiv, 2014 Personalised medicine strives to identify the right treatment for the right patient at the right time, integrating different types of biological and environmental information. Such information come from a variety of sources: omics data (genomic, proteomic, metabolomic, etc.), live molecular diagnostics, and other established diagnostics routinely used ...
arxiv
FEBS Letters, EarlyView.To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche +2 more
wiley +1 more source
Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine
Advances in Materials, 2019 Artificial intelligence (AI) and nanotechnology are two fields that are instrumental in realizing the goal of precision medicine—tailoring the best treatment for each cancer patient.
O. Adir +8 more
semanticscholar +1 more source