Trigeminal Nerve Asymmetry in Horses With Idiopathic Trigeminal-Mediated Headshaking: A Retrospective Case-Control Magnetic Resonance Imaging Study. [PDF]
Heun F+3 more
europepmc +1 more source
European Public Health NewsMartin McKee colomn9th EPH Conference—‘All for Health, Health for All’50 Years of Medicine Safety in the EU By Vytenis Andriukaitis, EU Commissioner for Health and Food SafetyMessage from the World Health Organization (WHO) Regional Director for Europe [PDF]
Dineke Zeegers Paget+3 more
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Investigation of CTX-M Type Extended-Spectrum β-Lactamase, Carbapenem and Colistin Resistance in Enterobacterales Isolated From Dairy Cattle in Turkey. [PDF]
Yalcin M+5 more
europepmc +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
The Evolution of Lifestyle Medicine Education: What, Why, How, Who, and What Now. [PDF]
Frates B.
europepmc +1 more source
Unveiling the Peril of Substandard and Falsified Medicines to Public Health and Safety in Africa: Need for All-Out War to End the Menace [PDF]
Nafiu Aminu+3 more
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source