Results 161 to 170 of about 9,199,416 (314)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Impact of Health-Related Social Needs on Transcatheter and Surgical Aortic Stenosis Treatment. [PDF]

JACC Adv
Sadri S, Amponsah D, Beyene TJ, Burdon TA, Fearon WF, Asch SM, Heidenreich PA, Yong CM.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Narrative medicine-inspired pedagogy for pathology residency: One pathology and laboratory medicine residency program's experience creating and implementing a narrative medicine-inspired curriculum as a component of didactics. [PDF]

Acad Pathol
Low D, Youngquist L, Reiter D, Glynn E, Pagano MB, Parker EU.   +5 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

ORGANIZATION OF MEDICAL SUPPORT OF MASS EVENTS ON EXPERIENCE OF THE FIELD MULTIPURPOSE HOSPITAL UNIT OF ALL-RUSSIAN CENTRE FOR DISASTER MEDICINE «ZASCHITA» IN 2018

Медицина катастроф, 2018
Chubaiko V.G. , Cheplyaev A.A., Chernyak S.I., Radchenko I.V., Grabchak S.A., Bobiy B.V., Savvin Y.N., Avetisov G.M.   +7 more
doaj  

Interplay between Genetic Ancestry, Self-reported Race and Ethnicity, and Clinical Factors in Pediatric Acute Lymphoblastic Leukemia: A REDIAL Consortium Report. [PDF]

Cancer Epidemiol Biomarkers Prev
Kore P, Geris JM, Leon-Camarena M, Castellanos MI, Taylor OA, Garcia-Morales V, Brown AL, Sok P, Schraw JM, Huynh V, Ludwig KF, Klesse LJ, Pruitt SL, Hughes AE, Tien K, Heym KM, Griffin T, Erana R, Bernini JC, Gramatges MM, Atkinson EG, Lupo PJ, Scheurer ME, Rabin KR.   +23 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

RESULTS OF SERVICE FOR DISASTER MEDICINE OF HEALTH MINISTRY OF THE RUSSIAN FEDERATION ACTIVITY IN 2017

Медицина катастроф, 2018
Chubayko V.G., Kryukov V.I., Baranova N.N., Belova A.B., Yuvakaev I.S., Radchenko I.V., Magazeyshchikova N.G.   +6 more
doaj  

INTERNATIONAL EXERCISES “LIQUIDATION OF MEDICAL AND SANITARY CONSEQUENCES OF EARTHQUAKES”, YEREVAN, REPUBLIC OF ARMENIA, DECEMBER, 4-8, 2018

Медицина катастроф, 2019
Tkhokhova Z.M., Cheplyaev A.A., Byzov A.V., Kalachyov I.I.   +3 more
doaj   +1 more source