Results 181 to 190 of about 5,062,841 (308)

Look-alike and sound-alike medicines: let us all be aware

, 2014
Sanjaya Mani Dixit
openalex   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

INFORMATION AND TELECOMMUNICATION TECHNOLOGIES IN ACTIVITIES OF SERVICE FOR DISASTER MEDICINE OF MINISTRY OF HEALTH OF RUSSIA

Медицина катастроф, 2019
Baranova N.N., Bobiy B.V., Goncharov S.F., Nazarenko G.I., Odintsov N.I.   +4 more
doaj   +1 more source

Bulk RNA-seq of skeletal muscle reveals the role of ZBED6 in sepsis-induced muscle atrophy in minipigs. [PDF]

Sci Data
Liu H, Shi W, Zheng Y, Yang S, Wang Y, Yang M, Yang Z, Mao E, Shang H, Chen E, Chen Y.   +10 more
europepmc   +1 more source

Market Access and Reimbursement Options For Orphan Durg Hospital Only Medicines In Europe – One Size Fits All?

, 2014
S. Vosgerau, Gernot Paulus, S. Plantoer
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Time-lapse imaging systems for embryo incubation and assessment to improve reproductive outcomes in women undergoing in vitro fertilisation: study protocol for an individual participant data meta-analysis of randomised controlled trials. [PDF]

BMJ Open
Bhide P, Chan DYL, Ahlström A, Del Campo L, Kieslinger D, Lundin K, Park H, Fauque P, Kahraman S, Khan KS, Kovacs P, Lambalk CB, Thangaratinam S, Vergouw CG, van Wely M, Zamora J.   +15 more
europepmc   +1 more source

Biomarker-guided personalised emergency medicine for all – hope for another hype?

, 2015
Philipp Schüetz, Drahomir Aujesky, Christian Müller, Beat P. Müller‐Stich   +3 more
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

[To all high school seniors considering medical education: better chose an alternative medicine practitioner or veterinary career!]. [PDF]

, 2013
Henning Fischer
openalex