Results 181 to 190 of about 26,876,580 (395)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

24. Pathology of Cholera, with an Exposition of the Causes that necessarily render all Medicine inoperative in that Disease [PDF]

n Toulmi
openalex   +1 more source

Does Evidence-Based Medicine Offer Fair Benefits for All? [PDF]

, 2004
Wendy Rogers
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine

Nature Reviews Cardiology, 2020
Elaheh Karbassi, Aidan M. Fenix, S. Marchianò, Naoto Muraoka, Kenta Nakamura, Xiulan Yang, C. Murry   +6 more
semanticscholar   +1 more source

Public Health in the 1980s and 1990s: Decline and rise? [PDF]

, 2006
Annotated and edited transcript of a Witness Seminar held on 12 October 2004. Introduction by Professor Virginia Berridge, London School of Hygiene and Tropical Medicine.First published by the Wellcome Trust Centre for the History of Medicine at UCL ...
Berridge, V, Christie, DA, Tansey, EM
core  

A book and website all IJE readers should know about * Forey B, Hamling J, Lee P, Wald N. International smoking statistics (2nd edition). A collection of historical data from 30 economically developed countries. Wolfson Institute of Preventive Medicine, Oxford: Oxford Medical Publications, 2002, pp. 854. 110. [PDF]

, 2004
Debbie A. Lawlor
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Maternal Care [PDF]

, 2001
This is the edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, London, on 6 June 2000. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2001.©The Trustee of the Wellcome ...
Christie, DA, Tansey, EM
core  

ALL HYPE, NO HOPE? EXCESSIVE PESSIMISM IN THE “ANTI-AGING MEDICINE” SPECIAL SECTIONS [PDF]

, 2005
Michael Rae
openalex   +1 more source