Results 61 to 70 of about 27,292,570 (391)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Assessment of Left Atrial Deformation and Function by 2-Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease [PDF]
, 2017 open7noBackground: The assessment of left atrial (LA) function by 2-dimensional speckle tracking echocardiography (STE) holds important clinical implications in human medicine. Few similar data are available in dogs.
Baron Toaldo, M. +6 more
core +2 more sources
Monaldi Archives for Chest Disease, 2020 We used a publicly available data of 44,672 patients reported by China’s centre for disease control to study the role of age, sex, co-morbidities and health-care related occupation on COVID-19 mortality.
Shahir Asfahan +5 more
doaj +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
"It isn't just consultants that need a BSc": student experiences of an Intercalated BSc [PDF]
, 2005 More medical schools are moving towards a compulsory intercalated BSc. These courses have not traditionally been aimed at those students interested in general practice and have tended to have limited clinical relevance.
Jones, M., Lloyd, M., Singh, S.
core
Cancers of unknown primary diagnosed during hospitalization: a population-based study [PDF]
, 2017 Background: Cancers of Unknown Primary (CUP) are the 3-4th most common causes of cancer death and recent clinical guidelines recommend that patients should be directed to a team dedicated to their care.
Allardice, Gwen +5 more
core +1 more source
ACE2 protein expression in lung tissues of severe COVID-19 infection
Scientific Reports, 2022 Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells. The level of ACE2 expression in the lung is hypothesised to correlate with an increased
Atish Gheware +17 more
doaj +1 more source
Human gene and disease associations for clinical‐genomics and precision medicine research
Clinical and Translational Medicine, 2020 We are entering the era of personalized medicine in which an individual's genetic makeup will eventually determine how a doctor can tailor his or her therapy.
Zeeshan Ahmed +3 more
semanticscholar +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Gender Bias in Nobel Prizes [PDF]
, 2018 Strikingly few Nobel laureates within medicine, natural and social sciences are women. Although it is obvious that there are fewer women researchers within these fields, does this gender ratio still fully account for the low number of female Nobel ...
Jauffred, Liselotte +2 more
core +3 more sources