Results 71 to 80 of about 26,997,198 (419)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine

open access: yesWorld Journal of Stem Cells, 2020
Mesenchymal stem cells (MSCs) are the most frequently used stem cells in clinical trials due to their easy isolation from various adult tissues, their ability of homing to injury sites and their potential to differentiate into multiple cell types ...
A. González-González   +4 more
semanticscholar   +1 more source

Prescription for the People: An Activist\u27s Guide to Making Medicine Affordable for All [PDF]

open access: yes, 2017
[Excerpt] Because every cure starts with an accurate diagnosis, in this book I explain how and why the current medicines system is dysfunctional and corrupt.
Quigley, Fran
core   +1 more source

Musculoskeletal disorders among doctors and nursing officers : an occupational hazard of overstrained healthcare delivery system in western Rajasthan, India

open access: yesBMC Musculoskeletal Disorders, 2023
Background The present study was conducted to estimate the prevalence and distribution of MSDs in different anatomical regions among Doctors and NO and to determine their ergonomic risk factors and predictors.
Diksha Mahajan   +10 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Allopathic Medicine’s Influence on Indigenous Peoples in the Kumaon Region of India [PDF]

open access: yes, 2018
This paper focuses on the use of western medicine in the Kumaon region of Uttarakhand, India. The goal of this research is to understand which healing practices are preferable in rural villages.
Blum, Eliana M
core   +1 more source

Medicinal plants used in the management of diabetes mellitus 2015 [PDF]

open access: yes, 2015
Diabetes mellitus is one of the common endocrine disorders prevalent in almost all of the countries. This chronic pathology is characterized by hyperglycemia caused by defective insulin action, insulin secretion, or the combination of both.
Ashafa, Anofi O. T.   +5 more
core   +4 more sources

F-18 FDG PET/CT in staging and response assessment of primary cutaneous diffuse large B-cell lymphoma (leg type)

open access: yesEuropean Journal of Hybrid Imaging, 2023
Primary cutaneous Diffuse Large B-Cell Lymphoma-leg type (PCDLBCL-LT) is a rare subtype of cutaneous lymphomas, with high frequency of extra-cutaneous relapse and poor prognosis.
Deepanksha Datta   +4 more
doaj   +1 more source

Diagnostic Evaluation of Non-Interpretable Results Associated with Gene in Genotype MTBDR Ver 2.0 [PDF]

open access: yesTuberculosis and Respiratory Diseases, 2020
Background Line probe assay (LPA) is standard diagnostic tool to detect multidrug resistant tuberculosis. Non-interpretable (NI) results in LPA (complete missing or light wild-type 3 and 8 bands with no mutation band in rpoB gene region) poses a ...
Binit Kumar Singh   +9 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

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