Results 151 to 160 of about 3,590,044 (385)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Precision medicine, an approach for development of the future medicine technologies

open access: yesIranian South Medical Journal, 2016
Precision medicine is an approach in medicine that takes into account individual differences in people's genes, environments, and lifestyle. This field of medicine redefines our understanding of disease onset and progression, treatment response, and ...
Iraj Nabipour, Majid Assadi
doaj  

Abstracts of Award-Winning Posters 8th Annual Health Sciences Poster Day, Faculty of Medicine, Health Sciences Centre Kuwait University, Kuwait, April 21, 2003 [PDF]

open access: bronze, 2003
Karel Kotaška   +70 more
openalex   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Evaluation of Some Aspects of Educational Inputs and Outputs of Community Medicine Departments in Iran Medical Sciences Schools and Universities [PDF]

open access: yes, 2012
Background: Human health is strongly related to economic, political, cultural, administrative and environmental conditions. Therefore, Medical sciences are not limited to biomedical sciences but also include social and psychological sciences.
Saadat Torabian , Abbas Vosugh Mogadam , Mojtaba Sedaghat Syahk,
core  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Plasmodium Vivax as a Causative Agent for Cerebral Malaria in a Group of Adults at Mizan Tepi Teaching Hospital: Case Series

open access: yesInternational Medical Case Reports Journal
Yosef Habtemariam,1 Molla Asnake,2 Misikr Alemu,3 Erkyehun Pawlos Shash,3 Tsegaw Worku Tessema,2 Zerubabel Girma Tesso,1 Michael Hawlet4 1School of Medicine, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan Aman, Ethiopia; 2School of
Habtemariam Y   +6 more
doaj  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy