Results 131 to 140 of about 2,434,425 (286)

Solberg named chair of MLS for UND School of Medicine and Health Sciences

, 2017
GRAND FORKS, N.D.—Brooke Solberg, PhD, associate professor and graduate program coordinator in the Department of Medical Laboratory Science (MLS) at the UND School of Medicine and Health Sciences (SMHS), has been named the new chair of the MLS department.
School of Medicine & Health Sciences
core   +1 more source

Structure-Based Repurposing of Clinically Approved Compounds for PDE-5 Inhibition: Integrative Computational and Pharmacokinetic Evaluation

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Background: Phosphodiesterase-5 (PDE-5) regulates intracellular cyclic guanosine monophosphate (cGMP) levels, modulating vascular smooth muscle tone.
Albashir Tahir, Yasir Idris Saleh, Ibrahim Khaleel Muazu   +2 more
doaj   +1 more source

Teaching and Learning during COVID-19 Crisis: Faculty Preparedness and Factors Influencing the Use of E-learning Platform at the College of Medicine and Health Sciences, University of Rwanda. [PDF]

Rwanda J Med Health Sci, 2022
Nyiringango G, Umubyeyi B, Nyirazigama A, Mukankusi J, Mukeshimana M, Mugarura J, Bagirisano J, Kayiranga D, Ryamukuru D, Igikundiro C, Rutayisire R, Niyikiza EM, Adejumo O.   +12 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Design and Mechanistic Investigation of Novel Metallodrugs: From Structure-Activity Relationships to Selective Cancer Cell Targeting

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
The relentless pursuit of alternatives to conventional platinum-based chemotherapeutics, hampered by severe side effects and drug resistance, defines a critical frontier in oncology drug discovery. This review consolidates and highlights the significance
Samad Khaksar, Nosrat Behzadi, Hasan Zakeri Zakeri, Peyman Salahshour, Sara Abdolmaleki   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Recent Updates on Orally Disintegrating Films Regarding Design, Characterization, and Assessment

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Orally disintegrating films (ODFs) are a pharmaceutical dosage form that liquefies or disintegrates rapidly in the mouth without water, creating an attractive option for patients with difficulty swallowing.
Asmaa Abdelaziz Mohamed, Firas Aziz Rahi   +1 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Impact of Erythropoietin Therapy on Inflammatory Biomarkers in Chronic Kidney Disease: A Comparative Study

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Background: Chronic kidney disease (CKD) is a progressive disorder frequently complicated by anemia and a persistent inflammatory state, both of which significantly contribute to morbidity and mortality.
Riyam Naji Al_Alwani, Jahanbakhsh Asadi, Zainab Mohammadi   +2 more
doaj   +1 more source

Ponce Health Sciences University School of Medicine

Academic Medicine, 2020
Georgina, Aguirre, Olga, Rodriguez de Arzola   +1 more
openaire   +3 more sources