Results 221 to 230 of about 3,903,678 (356)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Students' Assessment on the Patient Safety Education: The Case of College of Medicine and Health Sciences, University of Gondar.

Iran J Nurs Midwifery Res, 2020
Gudayu TW, Solomon AA.
europepmc   +1 more source

Achievements and Prospects of Juntendo University Institute of Health and Sports Science & Medicine

, 2020
Hisashi Naıto, Nobuto Shibata, Yuji Takazawa, Hidefumi Waki   +3 more
openalex   +2 more sources

Margaret Pelling and Scott Mandelbrote (eds), The practice of reform in health, medicine, and science, 1500–2000: essays for Charles Webster, Aldershot, Ashgate, 2005, pp. xv, 376 (hardback 0-7546-3933-9). [PDF]

, 2007
Keir Waddington
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Variations in Trauma Education Practices Across Emergency Medicine Residencies: Insights from a National Survey of Program Directors

Advances in Medical Education and Practice
Stephanie Stroever,1 Colten Lanning,2 Miloš Buhavac,3 Cameran Mecham,4 Andrea Weitz,4 Frank Frankovsky,2 Andres Rios,2 James Morris5 1Department of Medical Education, Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX, USA ...
Stroever S, Lanning C, Buhavac M, Mecham C, Weitz A, Frankovsky F, Rios A, Morris J   +7 more
doaj  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Perceived enablers and constraints of motivation to conduct undergraduate research in a Faculty of Medicine and Health Sciences: What role does choice play? [PDF]

PLoS One, 2019
Marais DL, Kotlowitz J, Willems B, Barsdorf NW, van Schalkwyk S.   +4 more
europepmc   +1 more source