Results 201 to 210 of about 4,033,374 (391)

Using Radial Shock Wave Therapy to Control Cerebral Palsy-Related Dysfunctions: A Randomized Controlled Trial [Letter]

open access: yesInternational Journal of General Medicine
Sumyia Mehrin Omar, Aboma Zewude Abdissa, Maryam Mohammed Bashir Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab EmiratesCorrespondence: Maryam Mohammed Bashir, Institute of Public
Omar SM, Abdissa AZ, Bashir MM
doaj  

Correction to: Assessment of Burnout Among Faculty Members at Mazandaran University of Medical Sciences and Its Association with Demographic Factors [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Aliye Zamani Kiasari1, Seyed Hamzeh Hosseini2, Nassim Ghahrani3, Siavash Moradi4, Seyedkhosro Ghasempouri5,6, Ehsan Abedini7. Atefe Zabihi Zazooli8, Fattane Amuei9 1Associate Professor, Department of Anesthesiology, Faculty of Medicine, Mazandaran ...
Aliye Zamani Kiasari   +7 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Evaluating Interprofessional Education Readiness and Perceptions Among Health Professions Students

open access: yesAdvances in Medical Education and Practice
Nouf Sulaiman Alharbi,1– 3 Nourah Mohammed Alenazi,4 Alaa Althubaiti,2,5 Reem Alkahtani,2,3,6 Seema Nasser,2,3,7 Marwh Gassim Aldriwesh2,3,8 1Department of Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences ...
Alharbi NS   +5 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Precision medicine, an approach for development of the future medicine technologies

open access: yesIranian South Medical Journal, 2016
Precision medicine is an approach in medicine that takes into account individual differences in people's genes, environments, and lifestyle. This field of medicine redefines our understanding of disease onset and progression, treatment response, and ...
Iraj Nabipour, Majid Assadi
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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