Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy [PDF]
Chronic neurohormonal and mechanical stresses are central fea-tures of heart disease. Increasing evidence supports a role forthe transient receptor potential canonical channels TRPC3 andTRPC6 in this pathophysiology.
Andersen, Asger +13 more
core +1 more source
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Helminth Induced Immunoregulation and Novel Therapeutic Avenue of Allergy
Birhanu Ayelign,1 Yonas Akalu,2 Banchamlak Teferi,3 Meseret Derbew Molla,4 Tewodros Shibabaw4 1Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar ...
Ayelign B +4 more
doaj
Amare Teshome Tefera,1 Biruk Girma,1 Aynishet Adane,2 Abebe Muche,3 Tadesse Awoke Ayele,4 Kefyalew Ayalew Getahun,5 Zelallem Aniley,1 Semira Ali,6 Simegnew Handebo7 1Department of Dentistry, School of Medicine, College of Medicine and Health Sciences ...
Tefera AT +8 more
doaj
A New Time of Reckoning, a Time for New Reckoning: Views on Health and Society, Tensions between Medicine and the Social Sciences, and the Process of Medicalization [PDF]
Diogo Silva da Cunha, Hélder Raposo
openalex +1 more source
The Role of Emergency Medicine Specialist on Performance of the Emergency Department of Kerman Shahid Bahonar Hospital: A Qualitative Study [PDF]
The Role of Emergency Medicine Specialist on Performance of the Emergency Department of Kerman Shahid Bahonar Hospital: A Qualitative Study Ghorbani Nia Rahil1*, Amiresmaeili MohammadReza2, NekoeiMoghadam Mahamod3, Saberi Nia Amin4 1.
Amiresmaeili, MohammadReza +3 more
core
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source
Medicine vendors: self-medication practices and medicine knowledge [PDF]
Background: Medicine vendors fill the gap created by inadequate skilled professionals required for medicine procurement, storage, and distribution in developing countries.
Auta, Asa +4 more
core +3 more sources
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher +8 more
wiley +1 more source
Community Level of COVID-19 Information Exposure and Influencing Factors in Northwest Ethiopia
Animut Tagele Tamiru,1 Bayew Kelkay Rade,1 Eden Bishaw Taye,2 Zelalem Nigussie Azene,3 Mehari Woldemariam Merid,4 Atalay Goshu Muluneh,4 Getahun Molla Kassa,4 Melaku Kindie Yenit,4 Asefa Adimasu Taddese,4 Kassahum Alemu Gelaye,4 Demiss Mulatu Geberu,5 ...
Tamiru AT +27 more
doaj

