Results 61 to 70 of about 2,161,810 (255)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Community Level of COVID-19 Information Exposure and Influencing Factors in Northwest Ethiopia

open access: yesRisk Management and Healthcare Policy, 2020
Animut Tagele Tamiru,1 Bayew Kelkay Rade,1 Eden Bishaw Taye,2 Zelalem Nigussie Azene,3 Mehari Woldemariam Merid,4 Atalay Goshu Muluneh,4 Getahun Molla Kassa,4 Melaku Kindie Yenit,4 Asefa Adimasu Taddese,4 Kassahum Alemu Gelaye,4 Demiss Mulatu Geberu,5 ...
Tamiru AT   +27 more
doaj  

Factors Associated with Length of Intensive Care Unit Stay Following Cardiac Surgery [Letter]

open access: yesResearch Reports in Clinical Cardiology, 2022
Abdul Moeed, Zunera Huda Department of Internal Medicine, Dow University of Health Sciences, Karachi, PakistanCorrespondence: Abdul Moeed, Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan, Tel +92-3061159372, Email ...
Moeed A, Huda Z
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Awareness Towards Corona Virus Disease (COVID-19) and Its Prevention Methods in Selected Sites in Wolaita Zone, Southern Ethiopia: A Quick, Exploratory, Operational Assessment

open access: yesRisk Management and Healthcare Policy, 2020
Eskinder Wolka, 1 Zewde Zema, 2 Melkamu Worku, 3 Kassahun Tafesse, 1 Antehun Alemayehu, 4 Kassahun Tekle Takiso, 5 Hailu Chare, 2 Lolemo Kelbiso 6 1Wolaita Sodo University College of Health Sciences and Medicine, School of Public Health, Sodo, Ethiopia;
Wolka E   +7 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Helminth Induced Immunoregulation and Novel Therapeutic Avenue of Allergy

open access: yesJournal of Asthma and Allergy, 2020
Birhanu Ayelign,1 Yonas Akalu,2 Banchamlak Teferi,3 Meseret Derbew Molla,4 Tewodros Shibabaw4 1Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar ...
Ayelign B   +4 more
doaj  

Oral Health Status of Hearing-Impaired Students Attending Special Need Schools in Amhara Region, Ethiopia: A Cross-Sectional Study

open access: yesClinical, Cosmetic and Investigational Dentistry, 2022
Amare Teshome Tefera,1 Biruk Girma,1 Aynishet Adane,2 Abebe Muche,3 Tadesse Awoke Ayele,4 Kefyalew Ayalew Getahun,5 Zelallem Aniley,1 Semira Ali,6 Simegnew Handebo7 1Department of Dentistry, School of Medicine, College of Medicine and Health Sciences ...
Tefera AT   +8 more
doaj  

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