Results 121 to 130 of about 6,795,603 (372)

IrGO: Iranian traditional medicine General Ontology and knowledge base. [PDF]

open access: yesJ Biomed Semantics, 2021
Naghizadeh A   +9 more
europepmc   +1 more source

Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study [PDF]

open access: yesarXiv, 2015
The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt pathway. In this chapter we use the Wnt pathway to showcase current mathematical and statistical techniques that enable modelers to gain insight into (models of) gene regulation,
arxiv  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Treatment planning with a 2.5 MV photon beam for radiation therapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi   +5 more
wiley   +1 more source

A study on the attitudes of foundation doctors in Malta towards general practice and their experience while working in the specialty [PDF]

open access: yes, 2018
Introduction: A substantial number of Foundation year (FY) doctors have a three month rotation in family medicine at the health centres in Malta. The aim of the study was to understand the factors that influence FY doctors’ attitudes towards general ...
Abela, Jurgen, Baldacchino, Marilyn
core  

Compartmental analysis of dynamic nuclear medicine data: models and identifiability [PDF]

open access: yes, 2016
Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue.
Delbary, Fabrice   +2 more
core   +2 more sources

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Impact of flexible noise control (FNC) image processing parameters on portable chest radiography

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract There is a lack of understanding in the performance of flexible noise control (FNC) processing, which is used in digital radiography on a scanner vendor and has four parameters each involving multiple options. The aim of this study was to investigate the impact of FNC on portable chest imaging. An anthropomorphic chest phantom was imaged using
Krystal M. Kirby   +6 more
wiley   +1 more source

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