Results 111 to 120 of about 6,719,287 (354)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Editorial: Methods in general cardiovascular medicine

Frontiers in Cardiovascular Medicine, 2023
Serafino Fazio, Silvia Marchiano, Coen van Solingen, Jin Li, Qingchun Zeng   +4 more
doaj   +1 more source

Management of Sleep Disorders in General Medicine

Psikiyatride Güncel Yaklaşımlar
Sleep is one of the fundamental cycles of human life, involving complex neurophysiological processes that are activated each night as the eyes close, and it has been a subject of curiosity since antiquity.
Gamze Baytar, Çiçek Hocaoğlu
doaj   +1 more source

Psychotherapy and the Problems of Values [PDF]

, 1974
The author is an assistant professor in the Department of Psychiatry, School of Medicine, Case Western Reserve University, Cleveland and Director of Outpatient Psychiatry Day-Clinic, Cleveland Metropolitan General Hospital. Dr.
Dulin, John T.
core   +1 more source

General Internal Medicine (GIM): do the Puzzle Pieces Portray the Picture? A Continuous Quality Improvement Process for Entrustable Professional Activities (EPAs)

, 2022
Samantha Halman, Laura Marcotte, Michelle Elizov, Lynfa Stroud, Jolanta Karpinski, Sharon E. Card   +5 more
openalex   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Assessment and analysis of H.pylori infection treatment strategies of St. Vincent Hospital\u27s family and internal medicine clinics [PDF]

, 2019
Helicobacter pylori is a gram-negative bacteria that is responsible for causing chronic gastritis, ulcers in the stomach and intestine, and eventually even gastric lymphoma or cancer.
Orr, Rebecca
core   +1 more source

Incidence of Drug-Drug Interactions among Patients Admitted to the Department of General Medicine in a Tertiary Care Hospital [PDF]

, 2018
Namrata Bajracharya, Ann Mary Swaroop, Saraswathy Ganesan Rajalekshmi, Viswam Subeesh, Eswaran Maheswari   +4 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Skin cancer patients profile at faculty of medicine university of North Sumatera pathology anatomy laboratory and Haji Adam Malik general hospital in the year of 2012-2015 [PDF]

, 2018
E K Sembiring, Delyuzar, Soekimin Soekimin   +2 more
openalex   +1 more source