Results 221 to 230 of about 6,257,987 (347)
Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis +17 morewiley +1 more sourceClinical impact of pharmacogenetic risk variants in a large chinese cohort. [PDF]
Nat CommunWei CY, Wen MS, Cheng CK, Sheen YJ, Yao TC, Lee SL, Wu JY, Tsai MF, Li LH, Chen CH, Fann CS, Yang HC, Huang YT, Chen HH, Liu YM, Yeh EC, Peng YC, Wang SJ, Chen SP, Tsai MT, Huo TI, Su CW, Tarng DC, Huang CC, Fuh JL, Lan KH, Liu YT, Lu CL, Lee YC, Huang YH, Li CP, Wang YF, Hsieh YC, Chen YM, Hsiao TH, Lin CH, Chen YJ, Chen IC, Mao CL, Chang SJ, Chang YL, Liao YJ, Lai CH, Lee WJ, Tung H, Yen TT, Yen HC, Chang JH, Huang CY, Chan L, Lin YW, Hsiao BY, Hu CJ, Lin YK, Lin YF, Chang TC, Wu DC, Kan JY, Hsu CY, Chen SC, Li CC, Huang CF, Sheu CC, Yang LJ, Chen CH, Chen KM, Chang SM, Liou MS, Wang SP, Lin KT, Chuang HP, Chen YJ, Sin J, Chen YT, Chang CC, Kuo CF, Lin JC, Kuo HC, Chan TM, Lee CW, Lai JH, Luo SF, Cheng HT, Lin LY, Chang LC, Tsai CT, Kao HL, Yu JJ, Jeng JS, Chiu MC, Hong TC, Yang SF, Lu HJ, Su SC, Chu P, Li PF, Tsai CL, Tsai CK, Tang SE, Lin CM, Wu YF, Huang CY, Ling SZ, Chang CC, Lin TK, Hsiao SM, Chang CH, Chen CD, Ma GC, Chang TY, Hwang JJ, Lu CL, Kao KJ, Hung CF, Chen SS, Chen PY, Tsui K, Chen YT, Chen CH, Chien CC, Chiang HS, Chiu YL, Chen HC, Kwok PY. +123 moreeuropepmc +1 more sourceEffects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials
Arthritis Care &Research, EarlyView.Objective
Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and fatigue. Almost everyone with fibromyalgia has sleep problems. We aimed to evaluate the effectiveness and safety of current interventions for the management of fibromyalgia‐related sleep problems.Jemma Hudson, Mari Imamura, Clare Robertson, Daniel Whibley, Lorna Aucott, Katie Gillies, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole K. Y. Tang, Gary J. Macfarlane, Miriam Brazzelli +11 morewiley +1 more sourceAmerican College of Rheumatology Guidance Statements for Addressing Mental Health Concerns in Youth With Pediatric Rheumatologic Diseases
Arthritis Care &Research, EarlyView.Objective
Pediatric rheumatologic diseases (PRDs) are characterized by high rates of anxiety and depression known to impact health‐related outcomes. We present guidance statements to assess and manage mental health concerns for youth with PRDs in pediatric rheumatology practice.Natoshia R. Cunningham, Ashley N. Danguecan, Samantha L. Ely, Yaa Amponsah, Alaina Davis, Suzanne Edison, Julia Harris, Jordan T. Jones, Alana Goldstein‐Leever, Alison Manning, Anne McHugh, Crystal Mui, Ekemini Ogbu, Nikki Reitz, Martha Rodriguez, Natalie Rosenwasser, Alyse Tankanow, Erin Treemarcki, Katherine Winner, Tamar B. Rubinstein, Andrea M. Knight, for the CARRA Mental Health Workgroup +21 morewiley +1 more source29-mRNA host response signatures for classification of bacterial infection, viral infection and disease progression in COVID-19 pneumonia: a post hoc analysis of the SAVE-MORE randomized clinical trial. [PDF]
Intensive Care Med ExpKyriazopoulou E, Kotsaki A, Safarika A, Poulakou G, Milionis H, Metallidis S, Adamis G, Fragkou A, Rapti A, Del Vecchio P, Kalomenidis I, Kitzoglou D, Angheben A, Kainis I, Iliopoulou K, Serino FS, Bakakos P, Tzavara V, Ioannou S, Dagna L, Dimakou K, Tzatzagou G, Chini M, Bassetti M, Kotsis V, Tsoukalas G, Selmi C, Nikolakopoulou S, Samarkos M, Doumas M, Masgala A, Papanikolaou I, Argyraki A, Akinosoglou K, Symbardi S, Panagopoulos P, Dalekos GN, Liesenfeld O, Sweeney TE, Khatri P, Giamarellos-Bourboulis EJ. +40 moreeuropepmc +1 more sourceJuvenile Idiopathic Arthritis, Earnings, and Work Loss: A Nationwide Matched Cohort Study
Arthritis Care &Research, EarlyView.Objective
This study compares trajectories of earnings and work loss in individuals with juvenile idiopathic arthritis (JIA) versus matched comparators from the general population. Methods
Patients with JIA (n = 4,737) were identified in the Swedish National Patient Register (2001–2017) and individually matched to up to five general population ...Heather Miller, Martin Neovius, Erik Sundberg, Johan Askling, Gustaf Bruze +4 morewiley +1 more source
