Results 51 to 60 of about 3,738,036 (312)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Homeopathy in veterinary medicine: general principles
Medicamentul Veterinar, 2007 Homeopathy therapeutic means are more significantly considered as an animals treatment alternative. This because homeopathy has in its view not only the fact that is harmless for animals, but also the important aspect of lack presence of residues in ...
Romeo T. Cristina
doaj
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
The Göktaş definition of family medicine/general practice. [PDF]
Aten Primaria, 2022 Göktaş O.
europepmc +1 more source
A pre and post intervention study to reduce unnecessary urinary catheter use on general internal medicine wards of a large academic health science center [PDF]
, 2018 Krista Wooller +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Factors associated with successful passage of the American College of Veterinary Internal Medicine general examination. [PDF]
J Vet Intern Med, 2022 Boudreaux B, Hill T.
europepmc +1 more source
Recent advances: General medicine [PDF]
BMJ, 1998 One review could not encompass all the noteworthy recent advances in general medicine, but research findings relevant to the treatment of HIV, congestive heart failure, prostatic hypertrophy, hypertension, hypercholesterolaemia, oestrogen replacement, osteoporosis, cancer screening, and symptoms of the common cold have generated particular interest.
openaire +2 more sources