Results 101 to 110 of about 2,199,020 (293)

Literature review on Perumpadu Rogam (Menorrhagia) in Siddha Medicine

Journal of Research in Traditional Medicine, 2018
BACKGROUND: Siddha Medicine is one of the Indigenous Medical Systems, which mentions about 4448 diseases affecting humans. Vatha, Pitha and Kapa (Three Humors) are the functional units of the human body.
Nithyapriya Sivaram, Thayalini Thileepan
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Informatics in Emergency Medicine: A Literature Review

Emergency Care and Medicine
In recent years, the integration of informatics in emergency medicine has led to significant improvements in clinical decision-making, patient management, and overall healthcare delivery.
Raffaele Conforti
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

THE USE OF MUD "TINAKSKAYA" IN MEDICINE (LITERATURE REVIEW)

Исследования и практика в медицине, 2016
This review summarizes the published data on the therapeutic properties of the mud "Tinakskaya". In addition, data on the use of natural factors lake "Therapeutic" in medicine is performed.
Z. A. Tsurigova, O. G. Chernikina, K. S. Elderova, L. V. Stepanyan, S. P. Sinchikhin   +4 more
doaj   +1 more source

Melancholy, its conceptual origin and development - Mind-Body relationship in ancient medicine and philosophy

, 2020
Melancholy is the concept originated from the humor theory which dominated the Western ancient medicine. Black bile was considered to cause various pathological states of body, in particular, abnormal changes in emotions and behaviors.
여인석
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Explainable artificial intelligence (XAI) in radiology and nuclear medicine: a literature review. [PDF]

Front Med (Lausanne), 2023
de Vries BM, Zwezerijnen GJC, Burchell GL, van Velden FHP, Menke-van der Houven van Oordt CW, Boellaard R.   +5 more
europepmc   +1 more source