Results 101 to 110 of about 4,228,613 (296)

Literature review on Perumpadu Rogam (Menorrhagia) in Siddha Medicine

open access: yesJournal of Research in Traditional Medicine, 2018
BACKGROUND: Siddha Medicine is one of the Indigenous Medical Systems, which mentions about 4448 diseases affecting humans. Vatha, Pitha and Kapa (Three Humors) are the functional units of the human body.
Nithyapriya Sivaram, Thayalini Thileepan
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Weighted Distributions: A Brief Review, Perspective and Characterizations [PDF]

open access: yes, 2017
The weighted distributions are widely used in many fields such as medicine, ecology and reliability, to name a few, for the development of proper statistical models.
Hamedani, Gholamhossein G.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

THE USE OF MUD "TINAKSKAYA" IN MEDICINE (LITERATURE REVIEW)

open access: yesИсследования и практика в медицине, 2016
This review summarizes the published data on the therapeutic properties of the mud "Tinakskaya". In addition, data on the use of natural factors lake "Therapeutic" in medicine is performed.
Z. A. Tsurigova   +4 more
doaj   +1 more source

Explainable artificial intelligence (XAI) in radiology and nuclear medicine: a literature review. [PDF]

open access: yesFront Med (Lausanne), 2023
de Vries BM   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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