Results 81 to 90 of about 2,199,020 (293)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Galen's Treatise Περὶ Ἀλυπίας (De indolentia) in Context [PDF]
, 2019 This volume offers a multi-disciplinary approach to the “new” Galen text De indolentia, discovered in 2005. It addresses Galen’s literary production, his medical and philosophical contribution, the Antonine plague, the reign of Commodus, and finally the ...
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Medicine sellers' perspectives on their role in providing health care in North-West Cameroon: a qualitative study. [PDF]
, 2012 BACKGROUND: Increasing recognition of the importance of medicine sellers in low-resource settings has emerged alongside assumptions that their motives and capacities primarily relate to profit maximization.
Mangham-Jefferies, LJ +3 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Literatura e medicina: o território partilhado
Cadernos de Saúde PúblicaPartindo do texto do escritor português José Cardoso Pires, "De Profundis: Valsa Lenta", em que o autor descreve a afasia pela qual passou em conseqüência de acidente vascular cerebral, são feitas considerações sobre o enfoque da doença por escritores e ...
Moacyr Scliar
doaj
Amyotrophic Lateral Sclerosis in Veterans: Review of the Scientific Literature
, 2006 The committee began its work by identifying the medicaland scientific literature on ALS. PubMed, a database created andmanaged by the National Library of Medicine, was searched forstudies on ALS in the veteran population.
Institute Of Medicine
core
Faculty Mentoring Practices in Academic Emergency Medicine
, 2017 Background Mentoring is considered a fundamental component of career success and satisfaction in academic medicine. However, there is no national standard for faculty mentoring in academic emergency medicine (EM) and a paucity of literature on the ...
Hockberger, Robert +7 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source