Results 121 to 130 of about 3,617,077 (391)

Personalized medicine in internal medicine

Clinical Medicine (Russian Journal), 2017
Personalized medicine - a new direction in medicine, which is based on the study of various biomarkers and the use of new methods of molecular analysis (primarily evaluating the activity of isoenzymes of cytochrome P450), allowing individualized approach to the selection of both the drugs and the selection of the dosing regimen for the purpose of ...
V G, Kukes, V F, Marinin, Yu V, Olefir, G V, Ramenskaya, N B, Lazareva, V V, Smirnov, M V, Zhuravleva, A B, Prokofiev, E V, Shih, A S, Zhestovskaia, N A, Rumyantsev, D V, Mandich, O A, Goroshko   +12 more
openaire   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

The human right to medicines [PDF]

, 2008
This article considers the component of the right to the highest standard of health that relates to medicines, including essential medicines. Using the right-to-health analytical framework that has been developed in recent years, the first section ...
Hunt, PH, Khosla, R
core  

Can student mental health nurses be prepared for medicines management? [PDF]

, 2014
Aim This paper reports on an evaluation of the Medicines with Respect project, which implemented a stepped approach to education and training in medicines management (MM) for mental health nurses (MHNs). Method In the retrospective qualitative study,
Hemingway S, Hemingway S, Mutsatsa S, Newell R, Turner J   +4 more
core   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Studies of medicines use by consumers

SHS Web of Conferences, 2012
One of the main aims of medicines’ use studies is to ensure rational use of them. Different types of medicines use studies exist – there are studies of medicines supply, consumption, behavior of medicines users and prescribers (advisers).
Salmane-Kulikovska I., Dobelniece S.
doaj   +1 more source

Submission to the United Nations Secretary General's High Level Panel on Access to Medicines [PDF]

, 2016
Much of the current debate on health care goals, medical innovation and trade rules focuses on the misalignment between the need to provide incentives to innovation – mainly through a tight intellectual property (IPR) regime – and the resulting negative ...
Kale, Dinar, Mackintosh, Maureen, Orsenigo, Luigi, Simonetti, Roberto   +3 more
core  

Compulsory Licensing of Patented Pharmaceutical Inventions: Evaluating the Options [PDF]

, 2009
In this Comment, the author traces the relevant legislative history pertaining to compulsory licensing of patented pharmaceuticals from the TRIPS Agreement of 1994 to the 2003 waiver to, and later proposed amendment of, article 31, which enables poor ...
Arezzo, Coco, Danzon, Danzon, Debrulle, Drahos, Drexl, Fox, Hovenkamp, Hovenkamp, Jerome H. Reichman, Love, Lybecker, Maskus, Mercurio, Mercurio, Moran, Outterson, Reichman, Reichman, Reichman, Watal, Yu   +22 more
core   +2 more sources

Multimorbidity and out-of-pocket expenditure on medicines: a systematic review

BMJ Global Health, 2018
Background Multimorbidity, the presence of two or more non-communicable diseases (NCD), is a costly and complex challenge for health systems globally. Patients with NCDs incur high levels of out-of-pocket expenditure (OOPE), often on medicines, but the ...
Grace Sum, T. Hone, R. Atun, C. Millett, M. Suhrcke, A. Mahal, G. Koh, J. Lee   +7 more
semanticscholar   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source