British Journal of Clinical Pharmacology, EarlyView.Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon +12 more
wiley +1 more source
An overview of the theta - S correlations in Fram Strait based on the MIZEX 84 data
Oceanologia, 2002 The water masses in Fram Strait have been analyzed on the basis of hydrographic casts taken in summer 1984 during the MIZEX 84 experiment. In particular, theta-S diagrams for 16 areas, each 5o in longitude and 1o in latitude, covering the strait from ...
Pawel Schlichtholz +1 more
doaj
The Marmara Sea Gateway since ~16 ky BP: non-catastrophic causes of paleoceanographic events in the Black Sea at 8.4 and 7.15 ky BP [PDF]
, 2007 The Late Quaternary history of connection of the Black Sea to the Eastern Mediterranean has been intensely debated. Ryan, Pitman and coworkers advocate two pulses of outflow from the Black Sea to the world ocean at ~16–14.7 ky BP and ~11–10 ky BP ...
Abrajano, T. +6 more
core
2005-2017 Ozone trends and potential benefits of local measures as deduced from air quality measurements in the north of the Barcelona metropolitan area [PDF]
, 2019 We analyzed 2005–2017 data sets on ozone (O3) concentrations in an area (the Vic Plain) frequently affected by the atmospheric plume northward transport of the Barcelona metropolitan area (BMA), the atmospheric basin of Spain recording the highest number
Alastuey, Andres +5 more
core +3 more sources
Distribution and mixing of intermediate water masses in the Channel of Sicily (Mediterranean Sea) [PDF]
Journal of Geophysical Research: Oceans, 2003 The Channel of Sicily, which represents the only connection between the western and the eastern Mediterranean Sea, can be described as a three‐layer system, where fresher water of Atlantic origin (Modified Atlantic Water) flows eastward in the upper layer, Levantine Intermediate Water (LIW) leaves the eastern basin at around 250–350 m, and an outflow ...
Daniele Iudicone +3 more
openaire +1 more source
The spread of non‐native species
Biological Reviews, EarlyView.ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock +16 more
wiley +1 more source
Estimation of mineral dust direct radiative forcing at the European Aerosol Research Lidar NETwork site of Lecce, Italy, during the ChArMEx/ADRIMED summer 2013 campaign: Impact of radiative transfer model spectral resolutions [PDF]
, 2016 © 2016. American Geophysical UnionA field campaign took place in the western and central Mediterranean basin on June–July 2013 in the framework of the ChArMEx (Chemistry-Aerosol Mediterranean Experiment, http://charmex.lsce.ipsl.fr/)/ADRIMED (Aerosol ...
Barragán Cuesta, Rubén +5 more
core +2 more sources
Subterranean environments contribute to three‐quarters of classified ecosystem services
Biological Reviews, EarlyView.ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola +30 more
wiley +1 more source
Atmospheric occurrence, transport and deposition of polychlorinated biphenyls and hexachlorobenzene in the Mediterranean and Black seas [PDF]
Atmospheric Chemistry and Physics, 2014 The Mediterranean and Black seas are unique marine environments subject to important anthropogenic pressures due to direct and indirect loads of atmospheric inputs of organochlorine compounds (OCls) from primary and secondary sources.
N. Berrojalbiz +5 more
doaj +1 more source
Upper ocean climate of the Eastern Mediterranean Sea during the Holocene Insolation Maximum – a model study [PDF]
, 2011 ine thousand years ago (9 ka BP), the Northern Hemisphere experienced enhanced seasonality caused by an orbital configuration close to the minimum of the precession index.
Adloff, F. +6 more
core +2 more sources