Results 91 to 100 of about 394,809 (281)

Effects of methamphetamine on locomotor activity and thalamic gene expression in leptin-deficient obese mice [PDF]

, 2017
Leptin is an adipose-derived hormone that regulates energy balance. Leptin receptors are expressed in extrahypothalamic sites and several reports showed that leptin can influence feeding and locomotor behavior via direct actions on dopaminergic neurons ...
Bisagno, Veronica, Gonzalez, Betina, Gonzalez, Candela Rocio, Urbano Suarez, Francisco Jose   +3 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

An investigation of planar array system artefacts generated within an electrical impedance mammography system developed for breast cancer detection [PDF]

, 2014
An Electrical Impedance Mammography (EIM) planar array imaging system is being developed at the University of Sussex for the detection of breast cancers.
Bilal, Rabia, Chatwin, Chris, Khan, Bilal, Young, Rupert   +3 more
core  

Comparing D-Bar and Common Regularization-Based Methods for Electrical Impedance Tomography [PDF]

, 2019
Objective: To compare D-bar difference reconstruction with regularized linear reconstruction in electrical impedance tomography. Approach: A standard regularized linear approach using a Laplacian penalty and the GREIT method for comparison to the D-bar ...
Adler, A., Hamilton, Sarah J., Lionheart, W.R.B.   +2 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Novel Solution for Overcoming Conflicts Between Line Protection and LVRT in MV Solar PV Interconnections

IEEE Access
The implementation of low-voltage-ride-through (LVRT) requirements for distributed generation (DG) sources in medium voltage (MV) distribution networks introduce challenges for the existing protection systems.
Anoop V. Eluvathingal, K. Shanti Swarup
doaj   +1 more source

Sensitivity-Based Model of Low Voltage Distribution Systems with Distributed Energy Resources

Energies, 2016
A key issue in Low Voltage(LV) distribution systems is to identify strategies for the optimal management and control in the presence of Distributed Energy Resources (DERs).
Anna Rita Di Fazio, Mario Russo, Sara Valeri, Michele De Santis   +3 more
doaj   +1 more source

State estimation applied to active distribution networks with minimal measurements [PDF]

, 2005
Traditionally, state estimation is applied to transmission networks to improve security and redundancy of the measurement system. This paper describes the application of state estimation to distribution networks in order to extend the observability of ...
Jenkins, Nick, Thornley, Vincent, White, Sara   +2 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Backward–forward sweep inverse power flow for distribution line parameters estimation with metering data

IET Smart Grid
The transition towards the smart grid requires better information on the electrical networks at the distribution system level. Information about electrical line parameters is a critical part of such information.
Pedro C. Leal, Pedro M. S. Carvalho
doaj   +1 more source