Results 101 to 110 of about 4,509,271 (313)

Global hydrological reanalyses: The value of river discharge information for world‐wide downstream applications – The example of the Global Flood Awareness System GloFAS

Meteorological Applications
Global hydrological reanalyses are modelled datasets providing information on river discharge evolution everywhere in the world. With multi‐decadal daily timeseries, they provide long‐term context to identify extreme hydrological events such as floods ...
Christel Prudhomme, Ervin Zsótér, Gwyneth Matthews, Angelique Melet, Stefania Grimaldi, Hao Zuo, Eleanor Hansford, Shaun Harrigan, Cinzia Mazzetti, Eric deBoisseson, Peter Salamon, Gilles Garric   +11 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

LncRNA-mediated early regulatory networks in sugar beet (Beta vulgaris L.) response to low nitrogen

BMC Genomics
Background Sugar beet (Beta vulgaris L.) is a globally important sucrose-producing crop. As a “nitrogen (N)-responsive species”, it specifically relies on precise N management to maximize agroeconomic potential.
Qing Bai, Kehua Chen, Haodi Ji, Yuanhang Zhou, Xiaodong Li, Dali Liu, Wang Xing   +6 more
doaj   +1 more source

Understanding Colletotrichum truncatum, a Pathogen of Soybean Anthracnose, and In Vitro Efficacy of Modern Fungicides for it’s Management

International Journal of Bio-Resource and Stress Management
The present investigation was convened during kharif, 2023 (July–December) at J.N.K.V.V., Jabalpur, Madhya Pradesh, India to characterize the fungus isolated from Anthracnose symptomatic sample of soybean, and to assess the fungal growth medium and ...
Priyanshi Raghuwanshi, Pawan Kumar Amrate, Sanjay Kharte, Kumar Jai Anand, Jayesh Sarkar, Lokhande Kiran Kisanrao, M. K. Shrivastava   +6 more
doaj   +1 more source

Movements of Media in Yvonne Rainer's Hand Movie (1966) and Richard Serra's Hand Catching Lead (1968)

The International Journal of Screendance, 2017
This article focuses on two experimental films from the 1960s: Yvonne Rainer’s Hand Movie (1966) and Richard Serra’s Hand Catching Lead (1968). It scrutinizes the way both works exhibit a hybridized and indeterminate approach to artistic media. It offers
Kyle Bukhari
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source