Structured triglycerides (STs) containing both medium-chain fatty acids (MCFA) and polyunsaturated fatty acids (PUFA) in the same molecule offer nutritional and therapeutic benefits.
Maria M. C. Feltes +5 more
doaj +1 more source
Comparison of the Effects of Coconut Oil and Soyabean Oil on TSH Level and Weight Gain in Rabbits [PDF]
The present study was conducted on 12 albino rabbits of either sex and weighing between 1-1.5kg to see the influence of coconut oil and soyabean oil on serum TSH levels and weight gain for a period of 12 weeks.
Bajwa, N, Gupta, S, Gupta, V, Walia, L
core +1 more source
Circulating micrornas associated with glycemic impairment and progression in Asian Indians. [PDF]
Aims/hypothesisAsian Indians have a high incidence of type 2 diabetes, but factors associated with glycemic progression in this population are not understood.
Aouizerat, Bradley E +3 more
core +1 more source
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang +10 more
wiley +1 more source
Lipid storage and autophagy in melanoma cancer cells [PDF]
Cancer stem cells (CSC) represent a key cellular subpopulation controlling biological features such as cancer progression in all cancer types. By using melanospheres established from human melanoma patients, we compared less differentiated melanosphere ...
Cordella, Martina +9 more
core +2 more sources
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen +14 more
wiley +1 more source
Adaptation to an MCFA-rich diet : effect on gastric tolerance, the capacity for MCFA oxidation, and performance while ingesting exogenous carbohydrate and structured oils during endurance exercise : a thesis presented in partial fulfilment of the requirements for the degree of Master of Sport Science at Massey University [PDF]
Introduction: Elevating the availability of fatty-acids to the muscle can potentially benefit endurance exercise performance by reducing intramuscular-glycogen utilisation. Digestion of triglycerides containing long-chain fatty acids (LCFAs) is slow, and
Thorburn, Megan
core
Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]
Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
core +1 more source
3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley +1 more source
Medium‐chain triglyceride (MCT) ketogenic therapy [PDF]
Summary The medium‐chain triglyceride diet (MCTD) is a variant of the classic 4:1 ketogenic diet (KD) introduced in 1971 by Huttenlocher as an attempt to improve the palatability of the KD by allowing more carbohydrates yet preserving ketosis. Although initially found to be equally effective as the classic KD, use of the MCTD declined because of ...
openaire +2 more sources

