Results 121 to 130 of about 3,446,771 (275)

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

Advanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu, Jiqing Wang, Zhiyun Hao, Mingna Li, Huimin Zhen, Yuan Liu, Guoyong Zhao, Chunyan Ren, Xuelan Zhou, Haixiong Hu, Mingjie Li, Nan Shi   +11 more
wiley   +1 more source

What is the role of medium‐chain triglycerides in the management of long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency?

, 2003
Cardiomyopathy is common in infants with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. Resolution of the cardiomyopathy can often be achieved by avoidance of fasting and changing from a conventional infant formula to one in which most long-chain
M. A. Dixon, Dixon, M. A., A. M. Lund, A. A. M. Morris, Morris, A. A.M., Lund, A. M., Leonard, J. V., P. Vreken, J. V. Leonard, Vreken, P.   +9 more
core   +1 more source

Lauric acid is a medium-chain fatty acid, coconut oil is a medium-chain triglyceride

, 2014
Based on biochemical and nutritional evidences, lauric acid (C12) has distinctive properties that are not shared with longer-chain saturated fatty acids: myristic acid (C14), palmitic acid (C16), and stearic acid (C18).
Dayrit, Fabian M
core   +1 more source

Consumer preference analysis on medium chain triglycerides (MCT) oil in the Philippines: A conjoint analysis

Future Foods
Medium-Chain Triglyceride (MCT) oil has gained popularity as a dietary supplement in the health and wellness industry, particularly for its potential health benefits and versatility in consumption.
Genard Paul R. Bajacan, Ardvin Kester S. Ong, John Francis T. Diaz, Maela Madel L. Cahigas, Ma.Janice J. Gumasing   +4 more
doaj   +1 more source

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source

Liquid–Liquid Equilibrium Data for Refined Olive Pomace Oil + Oleic Acid + Ethanol + Water Systems: Application to Solvent Deacidification

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT This study presents the first experimental liquid–liquid equilibrium (LLE) data for quaternary systems composed of refined olive pomace oil, oleic acid, ethanol, and water at 303.15 K. These data are essential for the design and optimization of solvent‐based deacidification processes, particularly for oils with high free fatty acid (FFA ...
Jacqueline Mansano Ortega, Andresa Feihrmann, Guilherme Duenhas Machado, Lucio Cardozo‐Filho, Francisco Adrian Sánchez, Vladimir Ferreira Cabral   +5 more
wiley   +1 more source

Gastrointestinal issues predominate among side effects of medium-chain triglyceride consumption in humans

Frontiers in Nutrition
IntroductionMedium-chain triglycerides (MCTs) are widely used in clinical and nutritional contexts due to their rapid metabolism and therapeutic potential.
Marc Scheller, Marius Frenser, Juliet Valembois, Tobias Fischer   +3 more
doaj   +1 more source

Optimizing Efficacy to Safety Ratio of Glucocorticoids in Rheumatoid Arthritis Models by Leveraging Peroxisome Proliferator–Activated Nuclear Receptor‐α Agonism

Arthritis &Rheumatology, EarlyView.
Objective Glucocorticoids remain essential therapies for immune and inflammatory diseases such as rheumatoid arthritis (RA) but are notorious for their metabolic side effects. Given the anti‐inflammatory and metabolically favorable actions of peroxisome proliferator–activated nuclear receptor (PPAR) agonists, we investigated whether PPARα agonism could
Lisa L. Koorneef, Elisabeth Gilis, Dorien Clarisse, Daria Fijalkowska, Sara Dufour, Julie Coudeneys, Bert Luyckx, Annick Verhee, Jonathan Thommis, Candice Vanden Bussche, Ulf Müller‐Ladner, Elena Neumann, Matthias Kerkhofs, Guillaume Planckaert, Simon Devos, Leander Meuris, Dirk Elewaut, Karolien De Bosscher   +17 more
wiley   +1 more source

Unveiling opportunities and challenges for a circular approach to macaúba biorefining: a technological roadmap

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The macaúba fruit, native to tropical and subtropical regions, has received considerable attention in recent years as a promising raw material for the production of advanced biofuels in Brazil. However, the development of large‐scale biomass requires overcoming significant challenges, such as designing circular biorefineries.
Fábio de A. Oroski, Flávia C. Alves, Maristela D. F. Freitas, José Vitor Bomtempo   +3 more
wiley   +1 more source

Acute effects of THC and a CBD+THC combination on cardiovascular haemodynamics and respiratory muscle activity during loaded breathing in healthy adults: A randomized placebo‐controlled crossover study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the acute effects of cannabidiol plus tetrahydrocannabinol (CBD+THC) and tetrahydrocannabinol (THC) oils on cardiovascular haemodynamics, respiratory muscle activity and peripheral tissue perfusion in healthy adults. Methods In this randomized, double‐blind, crossover trial, participants received orally administered ...
Edna Karla Ferreira Laurentino, Marina Lyra L. C. Fagundes, Bruno Lobão Soares, Rodrigo Torres‐Castro, Matias Otto‐Yañez, Emerson Arcoverde Nunes, Matheus Freitas Fernandes Pedrosa, Jéssica Danielle Medeiros da Fonsêca, Vanessa R. Resqueti, Guilherme Augusto de Freitas Fregonezi   +9 more
wiley   +1 more source