Results 171 to 180 of about 3,446,771 (275)

Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber

open access: yesiMeta, EarlyView.
This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu   +9 more
wiley   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

open access: yesiNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang   +5 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger   +3 more
wiley   +1 more source

Fat-Soluble Vitamin Supplementation Using Liposomes, Cyclodextrins, or Medium-Chain Triglycerides in Cystic Fibrosis: A Randomized Controlled Trial. [PDF]

open access: yesNutrients, 2021
Nowak JK   +12 more
europepmc   +1 more source

Application of current enteral nutrition support recommendations to infants born less than 750 grams or less than 25 weeks' gestation: A critical review

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Clinicians face a paucity of evidence‐based recommendations for provision of enteral nutrition in infants born <750 g or <25 weeks’ gestation, termed “nano‐preterm.” Current enteral nutrition recommendations for extremely low birth weight infants may not be broadly applicable to nano‐preterm infants due to physiological and developmental ...
Mar Romero‐Lopez   +4 more
wiley   +1 more source

A Comparative Study of Pain on Injection with Propofol Long-Chain Triglycerides Versus Propofol Medium/LongChain Triglycerides with Lignocaine

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth
Aadil S. Shah   +3 more
doaj   +1 more source

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