Results 221 to 230 of about 79,145 (285)

Insights Into Macrophage Ferroptosis: Implications for Atherosclerosis

open access: yesCell Proliferation, EarlyView.
Macrophage ferroptosis drives atherosclerosis by enhancing oxidative stress and inflammation, accelerating plaque progression and instability. Targeting macrophage ferroptosis presents a promising therapeutic strategy for atherosclerosis treatment.
Xiehui Chen, Xiangbo Liu, Changchun Zeng
wiley   +1 more source

Book Review: Medium Chain Triglycerides [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1969
openaire   +1 more source

Targeting inflammation in cardiometabolic disease: Icosapent ethyl modulates monocyte‐derived macrophages isolated from patients with cardiovascular disease with or without type 2 diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Despite intensive lipid‐lowering therapy, individuals with atherosclerotic cardiovascular disease (ASCVD) exhibit residual inflammatory risk, which drives recurrent cardiovascular events. This risk is amplified in type 2 diabetes mellitus (T2DM), where a pro‐inflammatory milieu accelerates atherogenesis. Monocyte‐derived macrophages (MDMs)
J. K. Ward   +4 more
wiley   +1 more source

Risk of acute pancreatitis with DPP‐4 inhibitors versus SGLT2 inhibitors in medication‐naïve individuals with diabetes: A target trial emulation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki   +3 more
wiley   +1 more source

An oral glucose tolerance test in pregnancy and its association with future cardiovascular diseases

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims/hypothesis Gestational diabetes and abnormal 100‐g oral glucose tolerance test (OGTT) results in pregnancy are associated with type 2 diabetes, but their relationship with cardiovascular disease (CVD) is less clear. We evaluated the risk of CVD according to the number of abnormal OGTT values during pregnancy.
Tal Schiller   +7 more
wiley   +1 more source

What Goes First? Effects of Starvation on the Body Condition of a Neotropical Dung Beetle

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We investigated how prolonged starvation affects key physiological traits in the dung beetle Dichotomius bos. Prolonged starvation leads to significant reductions in body dry mass and fat reserves, while muscle mass remains unchanged. These findings indicate that dung beetles prioritize the maintenance of locomotor muscles while mobilizing stored ...
Leonardo Vilas‐Bôas M. P. de Cerqueira   +5 more
wiley   +1 more source

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

open access: yesThe FEBS Journal, EarlyView.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna   +17 more
wiley   +1 more source

Cosmetic creams with caprylic acid‐based Natural Eutectic Solvents: Stability, rheology and user perception

open access: yesInternational Journal of Cosmetic Science, EarlyView.
By formulating creams with caprylic acid‐based hydrophobic Natural Eutectic Solvents and assessing their stability, rheological behaviour and sensory properties, this study demonstrates how these systems can act as multifunctional, COSMOS‐compliant ingredients that modulate emulsion characteristics without compromising formulation properties.
Alexis Verger   +7 more
wiley   +1 more source

Exploring the microbiota–skin–brain axis: Chicory extract biotransformed into a postbiotic neurocosmetic enhancer of social and sensory experience

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Application of CHICORY EXTRACT by a consumer has the ability to evoke positive emotional responses in individuals who come into tactile contact with the treated skin. Abstract Objective Measuring the influence of cosmetic ingredients on the microbiota‐skin‐brain axis is a difficult challenge.
Stefan Hettwer   +4 more
wiley   +1 more source

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