Results 61 to 70 of about 3,446,771 (275)

Mechanistic approach for the development of ultrafine oil-water emulsions using monoglyceride and blends of medium and long chain triglycerides: enhancement of the solubility and bioavailability of Perphenazine [PDF]

open access: yes, 2016
A kinetically stable ultra-fine oil-water (o/w) emulsion containing Perphenazine and blends of long and medium chain triglycerides was prepared. The purpose of the ultra-fine emulsion was to increase the oral bioavailability of Perphenazine.
Abdullah Gulam Mustafa   +3 more
core  

Additional file 1 of A multimodal analytical method to simultaneously determine monoacetyldiacylglycerols, medium and long chain triglycerides in biological samples during routine lipidomics

open access: yes, 2022
Additional file 1. A multimodal analytical method to simultaneously determine monoacetyldiacylglycerols, medium and long chain triglycerides in biological ...
Raymond H. Thomas (12528917)   +3 more
core   +1 more source

Nontraumatic chylothorax: Revisited

open access: yesJournal of Indian Association of Pediatric Surgeons, 2007
A 2-month-old girl came with breathlessness of 5 days′ duration. Clinical examination and plain chest radiograph showed it to be pleural effusion. On sonographically guided aspiration, the effusion fluid was found to be chyle.
Banerjee Debasish
doaj  

Coconut oil as a therapeutic treatment for alzheimer's disease: a review

open access: yesJournal of Future Foods, 2022
The coconut tree (Cocos nucifera) which is also known as the “Tree of life” has its own values in each part of the tree and coconut oil is more prestigious among them.
Poorni Sandupama   +2 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

open access: yesAdvanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen   +6 more
wiley   +1 more source

The impact of lipid-rich nutrition on ketogenesis and muscle weakness in sepsis

open access: yesIntensive Care Medicine Experimental
Background Administration of ketone bodies attenuated the severity of sepsis-induced muscle weakness in preclinical studies. Whether lipid-rich emulsions may likewise mitigate such muscle weakness by stimulating the endogenous ketogenic capacity remains ...
Caroline Lauwers   +9 more
doaj   +1 more source

中链甘油三酯中甘油二酯的分离与结构鉴定Isolation and identification of diglycerides from medium-chain triglycerides

open access: yesZhongguo youzhi
旨在阐明中链甘油三酯产品中的主要副产物甘油二酯类杂质的化学成分,以中链甘油三酯为原料,通过硅胶柱层析和半制备高效液相色谱法分离其中的甘油二酯,并通过核磁谱、质谱、红外光谱、紫外光谱和气相色谱对甘油二酯的结构进行鉴定。结果表明:从中链甘油三酯中分离出6种甘油二酯(DG-1~DG-6),结构依次被鉴定为1,3-二辛酸甘油二酯、1,2-二辛酸甘油二酯、1,3-辛酸癸酸甘油二酯、1,2-辛酸癸酸甘油二酯、1,3-二癸酸甘油二酯、1,2-二癸酸甘油二酯 ...
王国财,唐顺之,袁诚,李继荣,牟肖男,许文东王国财,唐顺之,袁诚,李继荣,牟肖男,许文东
doaj   +1 more source

Intestinal absorption and lymphatic transport of cholesterol in the rat: influence of the fatty acid chain length of the carrier triglyceride

open access: yesJournal of Lipid Research, 1969
This paper deals with the effect of the fatty acid chain length of dietary triglyceride on the intestinal uptake and lymphatic transport of exogenous and endogenous cholesterol in the rat.
Christer Sylvén, Bengt Borgström
doaj   +1 more source

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