Results 81 to 90 of about 6,254,868 (281)

Protein liquid chromatography /

open access: yes, 2000
Protein Liquid Chromatography is a handbook-style guide to liquid chromatography as a tool for isolating and purifying proteins, consisting of 25 individual chapters divided into three parts: Part A covers commonly-used, classic modes of chromatography ...
Kastner, Michael
core  

An on-line solid phase extraction procedure for the routine quantification of caspofungin by liquid chromatography-tandem mass spectrometry [PDF]

open access: yes, 2012
Background: Extensive sets of data are required to investigate the potential use of a therapeutic drug monitoring with individualization of dosage of the antimycotic compound caspofungin.
Rieger, Christina   +11 more
core   +1 more source

Chapter 23 - Modeling of preparative liquid chromatography

open access: yes, 2023
Preparative chromatography is the best generic method currently available for purifying small drugs and valuable chemical components at the 10-kg level.
Forssén, Patrik,   +2 more
core   +1 more source

3D‐Printed Actuator Powered by Liquid Crystal Elastomer Muscles at the Water–Air Interface

open access: yesAdvanced Materials Technologies, EarlyView.
Soft robots for unstructured environments require responsive, durable actuators. Liquid crystal elastomers (LCEs) provide large reversible deformations under thermal or optical stimuli. Direct ink writing enables fabrication of LCE actuators integrated with silicone, with mesogen chemistry and oligomers optimized for printable inks.
Cecilie Ryberg   +5 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

High-temperature open tubular liquid chromatography coupled to atmospheric pressure chemical ionisation mass spectrometry

open access: yes, 1996
A micro heated nebuliser interface was constructed and used for coupling of open tubular liquid chromatography at 150 degrees C to atmospheric pressure chemical ionisation mass spectrometry. For the chromatography, 50 mu m I.D.
Nyholm, LM,, Sjoberg, PJR, Markides, KE
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Isolation of Cinnamic Acid Derivatives from the Bulbs of Allium tripedale

open access: yesAdvanced Biomedical Research, 2018
Background: Allium genus with 750 species is the most diverse genus in the Amaryllidaceae family. Historically, Allium species have been used as medicinal plants, especially for prevention and treatment of cardiovascular diseases and considered as ...
Zahra Chehri   +2 more
doaj   +1 more source

Method transfer from high-pressure liquid chromatography to ultra-high-pressure liquid chromatography: II: Temperature and pressure effects

open access: yes, 2015
The importance of the generated temperature and pressure gradients in ultra-high-pressure liquid chromatography (UHPLC) are investigated and compared to high-pressure liquid chromatography (HPLC).
Cavazzini, Alberto,   +11 more
core   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

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