Results 131 to 140 of about 640,823 (337)

An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice. [PDF]

open access: yes, 2019
Chronic or excess glucocorticoid exposure causes lipid disorders such as hypertriglyceridemia and hepatic steatosis. Angptl4 (angiopoietin-like 4), a primary target gene of the glucocorticoid receptor in hepatocytes and adipocytes, is required for ...
Cheang, Rachel T   +11 more
core  

Navigating the Real World: A Scoping Review of Structured Frameworks to Effectively Identify, Evaluate, and Select Real‐World Data Sources for Fit‐for‐Purpose Studies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The potential of real‐world data (RWD), particularly from patient registries, has been increasingly recognized over the last decade by academia, regulators, and health technology assessment (HTA) bodies for its role in assessing a product's effectiveness and supporting regulatory submissions.
Sonia Zebachi   +13 more
wiley   +1 more source

The Prevalence of Eating Disorders and Disordered Eating in Adults Seeking Obesity Treatment: A Systematic Review With Meta‐Analyses

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To estimate the prevalence of eating disorders and disordered eating in adults seeking obesity treatment. Method Databases, MEDLINE, Embase, and PsycINFO, were searched to 20th March 2025. Studies reporting the prevalence of eating disorders or disordered eating at presentation to obesity treatment in adults (≥ 18 years) with ...
Hannah Melville   +8 more
wiley   +1 more source

Informetrics on accidents and trauma [PDF]

open access: yes, 1998
MEDLINE database has been analysed for 1995-97 on index Accidents and Trauma. Publications output has been classified year-wise country-wise, journal-wise and other fine structure characteristics have been found.
Kadam, S. N., Kalyane, V. L.
core  

Learning From Those Who Have Lived: A Scoping Review Exploring the Involvement of Lived Experience Co‐Design in Eating Disorder Research Methodologies

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective There is a growing demand in health research and policy to meaningfully involve people with lived experience in co‐creating research and treatment services, especially in eating disorders. Despite decades of research into risk, origin, onset, progression, and intervention, significant knowledge gaps remain. The aim of this review was
Jane Miskovic‐Wheatley   +6 more
wiley   +1 more source

How to search the medical literature

open access: yesCurrent Medicine Research and Practice, 2011
Searching the medical literature is often difficult and sometimes quite confusing. It is important to know the available databases and search tools along with their strengths and limitations.
Vivek Choudhary   +3 more
doaj  

Bibliometric Analysis of Research on Mental Health in the Workplace in Canada 1991-2002 [PDF]

open access: yes, 2003
This paper uses the Medline biomedical papers database to measure scientific production on mental health in the workplace (MHWP) during the 1991-2002 period at the world, Canadian, provincial, urban, institutional and researcher levels.
Archambault, Éric   +2 more
core  

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray   +2 more
wiley   +1 more source

Socio‐economic inequalities and heart failure morbidity and mortality: A systematic review and data synthesis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 927-941, April 2025.
Abstract Socio‐economic status (SES) has been associated with incident and prevalent heart failure (HF), as well as its morbidity and mortality. However, the precise nature of the relationship between SES and HF remains unclear due to inconsistent data. This study aims to provide a comprehensive assessment and data synthesis of the relationship between
Abdul Shakoor   +8 more
wiley   +1 more source

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