Results 181 to 190 of about 925,862 (377)

Real‐world effectiveness of targeted therapies in ATTR cardiomyopathy: A meta‐analysis integrating population‐based data

open access: yesESC Heart Failure, EarlyView.
Summary of the meta‐analysis evaluating the effectiveness of targeted therapies for transthyretin amyloid cardiomyopathy (ATTR‐CM). Pooled data from 10 studies (n = 5203) showed a 39% relative reduction in all‐cause mortality (RR: 0.61, 95% CI: 0.52–0.70).
Alexios S. Antonopoulos   +5 more
wiley   +1 more source

Individual Differences in Dopamine Are Associated with Reward Discounting in Clinical Groups But Not in Healthy Adults. [PDF]

open access: yes, 2019
Some people are more willing to make immediate, risky, or costly reward-focused choices than others, which has been hypothesized to be associated with individual differences in dopamine (DA) function.
Castrellon, Jaime J   +9 more
core   +1 more source

Minimization or withdrawal of oral pharmacotherapy in chronic heart failure patients with improved myocardial function: A systematic review

open access: yesEuropean Journal of Heart Failure, EarlyView.
This systematic review included seven studies that reported the outcomes of minimization or withdrawal of oral pharmacotherapy in chronic heart failure (HF) patients with improved myocardial function. There is a dearth of existing evidence, which supports only loop diuretic withdrawal and possibly carvedilol monotherapy.
Yuxiang Luo   +8 more
wiley   +1 more source

Evaluation of a Technology-Based Survivor Care Plan for Breast Cancer Survivors: Pre-Post Pilot Study. [PDF]

open access: yes, 2019
BACKGROUND: As of 2016, almost 16 million individuals were cancer survivors, including over 3.5 million survivors of breast cancer. Because cancer survivors are living longer and have unique health care needs, the Institute of Medicine proposed a ...
Barsevick, Andrea   +11 more
core   +1 more source

Using Cenobamate for managing idiopathic generalized epilepsy: A single‐center experience and systematic literature review

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate the single‐center experience of Cenobamate's (CNB) off‐label use in adults with idiopathic generalized epilepsy (IGE). Methods We conducted a retrospective review of electronic health records within a large healthcare system to identify IGE patients prescribed CNB.
Nicole Woodrich   +4 more
wiley   +1 more source

We do our work with all our heart

open access: yesJournal of Arrhythmia, 2015
İsmail Ateş   +2 more
doaj   +1 more source

Prevalence and incidence of infantile epileptic spasms syndrome in India: A systematic review and meta‐analysis

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Infantile epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy of infantile onset. While epidemiological data from Western countries and global estimates are available, consolidated evidence on the burden of IESS in India remains limited.
Akanksha Singh   +6 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

open access: yesFood Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima   +15 more
wiley   +1 more source

The Performance of Automatic Speaking Valves and Fixation Devices Enabling Hands‐Free Speech Following Total Laryngectomy—A Systematic Review

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The percentage of daily automatic speaking valve use (AU) in laryngectomized patients has remained at ~25% since their invention. To increase this percentage, understanding the performance of existent devices is essential. Therefore, we reviewed studies reporting AU, fixation device lifetime (FDL), compliance, and voice and speech ...
Max J. Dullaart   +9 more
wiley   +1 more source

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