Results 51 to 60 of about 701,729 (307)
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Adherence to the International Committee of Medical Journal Editors–recommended gender equity policy in nursing journals listed in MEDLINE or PubMed Central: a descriptive study [PDF]
Science EditingPurpose The evolving landscape of nursing research emphasizes inclusive representation. The International Committee of Medical Journal Editors (ICMJE) has established guidelines to ensure the fair representation of various demographic variables ...
Eun Jeong Ko, Geum Hee Jeong
doaj +1 more source
AGING MEDICINE, EarlyView.Deprescribing interventions in primary care modestly reduce medication burden, patient falls, and hospitalisations among older adults, highlighting the value of medication reviews and collaborative care strategies. ABSTRACT Background Deprescribing is a systematic approach aimed at reducing the number of medications that are no longer beneficial or ...
Christina Malini Christopher +6 more
wiley +1 more source
Bone & Joint OpenAims: The aim of this study was to perform a systematic review and bias evaluation of the current literature to create an overview of risk factors for re-revision following revision total knee arthroplasty (rTKA).
Julius T. Hald +5 more
doaj +1 more source
Bone & Joint Open, 2023 Aims: The aim of this study was to determine the effectiveness of home-based prehabilitation on pre- and postoperative outcomes in participants awaiting total knee (TKA) and hip arthroplasty (THA).
Talitha C. De Klerk +4 more
doaj +1 more source
Discrepancies in Written Versus Calculated Durations in Opioid Prescriptions: Pre-Post Study. [PDF]
, 2020 BACKGROUND: The United States is in the midst of an opioid epidemic. Long-term use of opioid medications is associated with an increased risk of dependence. The US Centers for Disease Control and Prevention makes specific recommendations regarding opioid
Babula, Bracken +6 more
core +1 more source
Changes in heart rate and heart rate variability as a function of age in Thoroughbred horses. [PDF]
, 2017 We investigated changes in heart rate (HR) and HR variability as a function of age in newborn foals to old Thoroughbred horses. Experiments were performed on a total of 83 healthy and clinically normal Thoroughbred horses.
Jones, James H, Ohmura, Hajime
core +1 more source
Annals of Gastroenterological Surgery, EarlyView.This systematic review and meta‐analysis evaluated the role of primary tumor resection (PTR) in asymptomatic patients with unresectable metastatic colorectal cancer. Across 17 eligible studies including 9317 patients, PTR did not improve overall or progression‐free survival compared with chemotherapy alone.
Junpei Takashima +3 more
wiley +1 more source
Building Data-Driven Pathways From Routinely Collected Hospital Data:A Case Study on Prostate Cancer [PDF]
, 2015 Background: Routinely collected data in hospitals is complex, typically heterogeneous, and scattered across multiple Hospital Information Systems (HIS).
Adriansyah, A +8 more
core +2 more sources
Annals of Gastroenterological Surgery, EarlyView.This systematic review and meta‐analysis of 38 studies, encompassing over 5000 patients, compared extralevator abdominoperineal excision (ELAPE) with standard abdominoperineal excision (APE) in patients with advanced low rectal cancer. ELAPE was associated with significantly improved overall and disease‐free survival, reduced intraoperative perforation
Sarolta Beáta Kávási +7 more
wiley +1 more source