Results 151 to 160 of about 230,318 (346)

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source

HIDF: Integrating Tree‐Structured scRNA‐seq Heterogeneity for Hierarchical Deconvolution of Spatial Transcriptomics

Advanced Science, EarlyView.
The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou, Yuting Bai, Bo Wang, Wanwan Shi, Xiao Liang, Jiawei Luo   +5 more
wiley   +1 more source

On the Basal Rate of the Denervated Heat of Dogs before and after Inactivation of the Suprarenal Medulla

, 1935
Masao Wada, Zyumpei Kanowoka
openalex   +2 more sources

Treatment strategy for the tumor cyst of the medulla in an eloquent area: a case report and review of the literature

, 2021
Volodymyr Fedirko, Andrii G. Naboichenko, Mykola V. Iehorov, Albina Tretiakova, Oleksandra Y. Malysheva   +4 more
openalex   +2 more sources

Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD

Advanced Science, EarlyView.
Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du, Yinming Li, Rong Wu, Yufei Shen, Jiayi Yang, Xuan Xiao, Yu Zhou   +6 more
wiley   +1 more source

Variability of the medullary arcuate nucleus in humans [PDF]

, 2018
Ferrero, S, Lavezzi, Am, Paradiso, B, Thiene, G   +3 more
core   +1 more source

Compression of the Medulla due to the Dolichoectatic Vertebral Artery and Auditory and/or Vestibular Symptoms

, 2003
Shigeto Nakashima
openalex   +2 more sources

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Changes in cyclic nucleotide levels in the catecholamine release from dog adrenal medulla

, 1977
Katsuya Morita, Takashige Nishikawa, Akira Tsujimoto   +2 more
openalex   +1 more source

IMMUNOHISTOCHEMICAL CHARACTERISTICS OF STRUCTURAL CHANGES IN THE CORTEX AND MEDULLA OF THE ADRENAL GLANDS UNDER THE INFLUENCE OF A FOOD ADDITIVE COMPLEX [PDF]

, 2023
S. V. Donchenko, С. М. Білаш
openalex   +1 more source