Results 41 to 50 of about 44,526 (207)

Shared molecular pathways in pediatric genetic epilepsies: Insights from a single‐center cohort of 80 patients

Epilepsia Open, EarlyView.
Abstract Objective Genetic epilepsies in childhood are highly heterogeneous, and approaches to identify shared biological mechanisms across distinct genetic etiologies remain limited. We aimed to investigate whether genes associated with pediatric genetic epilepsies in our heterogeneous cohort converge on common functional pathways.
Laura Hecher, Mathias Woidy, Franziska Plein, Tatjana Bierhals, Leonie von Elsner, Theresia Herget, Maja Hempel, Fanny Kortüm, Lev Grinstein, Julia V. Cramer, Jessika Johannsen, Jonas Denecke   +11 more
wiley   +1 more source

Attention-deficit hyperactivity disorder in spontaneously hypertensive rat strain SHR/NCrl is associated with specific expression of uncoupling proteins, glucose transporter 1 and BACE1

Frontiers in Cellular Neuroscience
Attention-deficit hyperactivity disorder (ADHD) is the most prevalent neurodevelopmental disorder worldwide. To improve treatment strategies against ADHD a better understanding of underlying pathophysiology is required.
Tsunehisa Sato, Tsunehisa Sato, Rolf Schreckenberg, Klaus-Dieter Schlüter   +3 more
doaj   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source

Role of Medullary AKT and p38 MAPK in Regulating Feeding of Broiler Chicks

The Journal of Poultry Science
In layer chicks, central administration of insulin and refeeding promote the phosphorylation of AKT and extracellular signal-regulated kinase (ERK) in the medulla oblongata. Broiler chicks consume more feed than layer chicks, suggesting
Takaoki Saneyasu, Miyu Kaihatsu, Kanami Nagata, Aika Kitayama, Haruka Sakai, Hiroshi Kamisoyama, Junya Takegaki, Kazuhisa Honda   +7 more
doaj   +1 more source

Evidence of internal structure validity of the nursing outcome “Mechanical Ventilation Weaning Response: Adult (0412)” for critically ill COVID‐19 patients

International Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To evaluate the evidence of internal structure validity of the nursing outcome (NO) “Mechanical Ventilation Weaning Response: Adult (0412)” of the NOs classification for critically ill COVID‐19 patients. Methods A methodological study focused on internal structural validation, part of a multicenter study, was carried out in the ...
Aline Batista Maurício, Viviane Martins da Silva, Agueda Maria Ruiz Zimmer Cavalcante, Larissa Giardini Bruni, Sue Ann Moorhead, Elizabeth Swanson, Karen Dunn Lopez, Marcos Venícios de Oliveira Lopes, Alba Lucia Bottura Leite de Barros   +8 more
wiley   +1 more source

Different distribution of neuromedin S (NMS) and its mRNA in the rat brain: NMS peptide is present not only in the hypothalamus as the mRNA, but also in the brainstem

Frontiers in Endocrinology, 2012
Neuromedin S (NMS) is a neuropeptide identified as another endogenous ligand for two orphan G protein-coupled receptors, FM-3/GPR66 and FM-4/TGR-1, which have also been identified as types 1 and 2 receptors for neuromedin U structurally related to NMS ...
Miwa eMori, Kenji eMori, Takanori eIda, Takahiro eSato, Masayasu eKojima, Mikiya eMiyazato, Kenji eKangawa   +6 more
doaj   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

In Vitro Examination of Ontogenesis of Developing Neuronal Cells in Vagal Nuclei in Medulla Oblongata in Newborns

Biomolecules & Biomedicine, 2008
The development of neuron cells in vagal nerve nuclei in medulla oblongata was studied in vitro in live newborns and stillborns from different cases.
Hilmi Islami, Ragip Shabani, Sadi Bexheti, Ibrahim Behluli, Aziz Šukalo, Denis Raka, Rozafa Koliqi, Naim Haliti, Hilmi Dauti, Shaip Krasniqi, Mentor Disha   +10 more
doaj   +1 more source

Neuropathology of a patient with Parkinson's disease and biallelic expansion in RFC1

Brain Pathology, EarlyView.
This is the first report of neuropathology in biallelic RFC1 expansion‐associated Parkinson’s disease (PD). It shows a synucleinopathy of intraneuronal Lewy bodies consistent with the clinical PD diagnosis while neuropathological CANVAS (Cerebellar Ataxia with Neuropathy and bilateral Vestibular Areflexia) features were absent.
Jussi Sipilä, Tuomas Rauramaa, Laura Kytövuori, Kari Majamaa   +3 more
wiley   +1 more source

On the propagation of inhibitory excitation in the medulla oblongata

, 1882
ON THE PROPAGATION OF INHIBITORY EXCITATION IN THE MEDULLA OBLONGATA On the propagation of inhibitory excitation in the medulla oblongata (33) (-
Kronecker, Hugo Samuel James Meltzer
core   +3 more sources