Results 51 to 60 of about 44,526 (207)

Surgical application of the suboccipital subtonsillar approach to reach the inferior half of medulla oblongata tumors in adult patients

open access: yesFrontiers in Surgery, 2016
Medulla oblongata tumors are uncommon in adults. Controversies about their treatment arise regarding the need for histologic diagnosis in this eloquent area of the brain, weighing benefits of a reliable diagnosis and the potential disadvantages of ...
Alejandra T Rabadán   +2 more
doaj   +1 more source

Chronic traumatic encephalopathy in a neuropathologically confirmed Creutzfeldt–Jakob disease cohort

open access: yesBrain Pathology, EarlyView.
Systematic neuropathological screening of 212 patients with Creutzfeldt–Jakob disease (55% women) identified chronic traumatic encephalopathy in three cases (1.4%), all men with a history of contact sports. These findings represent the first neuropathologically confirmed chronic traumatic encephalopathy cases reported in Spain.
Lluc Bertran   +13 more
wiley   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Localization of the physiological prion and Na+–K+ ATPase activity in tissues of rats prion-replicating system

open access: yesБіологічні студії, 2011
Immunohistochemical studies of prion-replicating tissues, in six months rats, showed presence of the physiological prion in small intestine, particularly in cells of the jejunum villi own plate – lymphocytes and monocytes.
M. V. Kushkevych   +2 more
doaj   +1 more source

Computed tomography reveals the endocranial anatomy of Crocodylia: Implications for phylogenetic relationships and ecomorphological convergence across Crocodylomorpha

open access: yesJournal of Anatomy, EarlyView.
The evaluation of the endocranial anatomy of 43 crocodylian species reveals several differences, including variation in the curvature of the encephalic endocast, the size of the endosseous labyrinth and paratympanic sinuses, and the presence of additional snout sinuses.
Paul M. J. Burke, Philip D. Mannion
wiley   +1 more source

Proposed operative approach in a critical area of the brain stem

open access: yesInterdisciplinary Neurosurgery
Background and importance: The surgical approach to the medulla oblongata poses a significant challenge for neurosurgery, considering the clinical consequences and risks of this procedure. The authors describe a step-by-step technique to safely extirpate
Boris Zurita-Cueva   +4 more
doaj   +1 more source

A Case of Adult-Onset Alexander Disease Featuring Severe Atrophy of the Medulla Oblongata and Upper Cervical Cord on Magnetic Resonance Imaging

open access: yesCase Reports in Neurology, 2012
Adult-onset Alexander disease (AOAD) has been increasingly recognized since the identification of the glial fibrillary acidic protein gene mutation in 2001.
Tadahiro Yonezu   +5 more
doaj   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli   +12 more
wiley   +1 more source

Medullary infarction with central facial paralysis as the only symptom: a case report

open access: yesJournal of International Medical Research
The anatomical structure of the medulla oblongata is complex, its nerve fibers are dense, and its blood vessels are complex. Clinical manifestations of ischemic damage to the medulla oblongata are therefore relatively diverse, and include vertigo ...
Ruiqi Tian   +3 more
doaj   +1 more source

A convenient three dimensional model to teach the arterial supply of the brainstem

open access: yesArtery Research, 2009
An easier approach of teaching the three dimensional nature of arteries of the brainstem is being proposed and aids the understanding of clinical vascular conditions of the brain.
H. Gangata
doaj   +1 more source

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