Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells [PDF]
Thymic medullary regions are formed in neonatal mice as islet-like structures, which increase in size over time and eventually fuse a few weeks after birth into a continuous structure.
R. Satoh +12 more
semanticscholar +2 more sources
Current Guidelines for Management of Medullary Thyroid Carcinoma [PDF]
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor originating from the parafollicular cells. The diagnostic and therapeutic strategies for the condition are different from those used for well-differentiated thyroid cancer.
Mijin Kim, Bo Hyun Kim
doaj +1 more source
Trends in the Diagnosis and Treatment of Patients with Medullary Thyroid Carcinoma in Korea [PDF]
Background Thyroid cancer is becoming increasingly common worldwide, but little is known about the epidemiology of medullary thyroid carcinoma (MTC). This study investigated the current status of the incidence and treatment of MTC using Korean National ...
Hwa Young Ahn +5 more
doaj +1 more source
Medullary Thyroid Cancer: Updates and Challenges
A personalized approach to the management of medullary thyroid cancer (MTC) presents several challenges; however, in the past decade significant progress has been made in both diagnostic and treatment modalities. Germline rearranged in transfection (RET)
M. Gild +3 more
semanticscholar +1 more source
Recently, selpercatinib, a highly selective inhibitor of RET receptor tyrosine kinase, has been used for RET-altered thyroid cancer. We present four cases of patients with advanced thyroid cancer who were treated with selpercatinib. The first patient was
Han-Sang Baek +5 more
doaj +1 more source
Navigating the Current Landscape of Non-Clear Cell Renal Cell Carcinoma: A Review of the Literature
Non-clear cell renal cell carcinoma (nccRCC) is an entity comprised of a heterogeneous constellation of RCC subtypes. Genomic profiling has broadened our understanding of molecular pathogenic mechanisms unique to individual nccRCC subtypes.
Alexius John +2 more
doaj +1 more source
Multiple endocrine neoplasia type 2B: A genotype-phenotype diagnostic and therapeutic approach
Multiple endocrine neoplasia type 2B (MEN 2B) is a rare genetic syndrome with an estimated prevalence of 0.9 to 1.6 per million individuals and an annual incidence of 1.4 to 2.6 per million live births.
Valentina Agredo Delgado +2 more
doaj +1 more source
Mixed medullary—papillary thyroid carcinoma with mixed lymph node metastases: A case report
Mixed medullary‐follicular‐derived carcinoma is a very rare event. It is extremely important to make the correct diagnosis, due to prognostic and treatment implications. A genetic study of these patients is advisable to exclude the presence of MEN 2.
Vanessa Guerreiro +8 more
doaj +1 more source
Histopathological and immunohistochemical features of thyroid carcinoma [PDF]
Thyroid-specific malignant tumors are derived from follicle cells (papillary and follicular carcinoma), and from parafollicular, calcitonin-producing C-cells (medullary carcinoma). The main criterion for diagnosis of papillary carcinoma is the occurrence
Tatić Svetislav B.
doaj +1 more source
Radionuclide therapy in the treatment of thyroid malignancy [PDF]
In this paper we presented the principles of performance of radionuclide therapy, its adverse effect, together with mentioned complications obligation to use it only according to directions and the success of the therapy, which is seen through the length
Malešević Milica Đ.
doaj +1 more source

