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Thyroid: Medullary carcinoma [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Medullary thyroid cancers (MTC) are rare neuroendocrine tumors arising from the parafollicular C-cells of the thyroid. In this review, we provide a general overview of the classification, pathology, and clinical management of MTC. In the latter half, we survey the underlying genetic framework of MTC and its potential implications within a diagnostic ...
Somnay, Y, Schneider, D, Mazeh, H
openaire   +5 more sources

Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait [PDF]

Urology Case Reports, 2015
Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature.
Piergiuseppe Colombo, Steven C. Smith, Simona Massa, Salvatore L. Renne, Simona Brambilla, Roberto Peschechera, Pierpaolo Graziotti, Massimo Roncalli, Mahul B. Amin   +8 more
doaj   +2 more sources

Medullary thyroid carcinoma [PDF]

Clinical Endocrinology, 2004
SummaryMedullary thyroid carcinoma (MTC) arises from parafollicular or C cells that produce calcitonin (CT), and accounts for 5–10% of all thyroid cancers. MTC is hereditary in about 25% of cases. The discovery of a MTC in a patient has several implications: disease extent should be evaluated, phaeochromocytoma and hyperparathyroidism should be ...
Sophie, Leboulleux, Eric, Baudin, Jean-Paul, Travagli, Martin, Schlumberger   +3 more
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Synchronous mixed medullary‐papillary carcinoma and papillary multifocal carcinoma of the thyroid with cervical lymph node metastases

Clinical Case Reports, 2023
Key Clinical Message The occurrence of simultaneous multifocal papillary thyroid carcinoma and mixed medullary‐papillary carcinoma, as far as we know, has not been previously described.
Raquel Lalanda, David Aparício, João Boavida, Dolores Lopes Presa, Lucas Batista, Luís Miranda   +5 more
doaj   +1 more source

Susceptibility Genes and Chromosomal Regions Associated With Non-Syndromic Familial Non-Medullary Thyroid Carcinoma: Some Pathogenetic and Diagnostic Keys

Frontiers in Endocrinology, 2022
Thyroid cancer is the malignant tumor that is increasing most rapidly in the world, mainly at the expense of sporadic papillary thyroid carcinoma. The somatic alterations involved in the pathogenesis of sporadic follicular cell derived tumors are well ...
María Sánchez-Ares, Soledad Cameselle-García, Ihab Abdulkader-Nallib, Ihab Abdulkader-Nallib, Gemma Rodríguez-Carnero, Carolina Beiras-Sarasquete, José Antonio Puñal-Rodríguez, José Antonio Puñal-Rodríguez, José Manuel Cameselle-Teijeiro, José Manuel Cameselle-Teijeiro   +9 more
doaj   +1 more source

Rare Mixed Thyroid Carcinomas: A Report of Two Cases [PDF]

Iranian Journal of Otorhinolaryngology, 2022
Introduction:Thyroid cancers constitute 0.5%- 1% of all cancers of which differentiated cancers are most common. Mixed thyroid carcinomas are rare entities comprising only 0.5% of thyroid cancers. These tumours pose challenges in diagnosis by fine needle
Nitya Subramanian, Sangeet Kumar Agarwal, Alok Agarwal, Pallav Gupta   +3 more
doaj   +1 more source

Renal medullary carcinoma masquerading as renal infection: a case report

BMC Nephrology, 2020
Background Renal medullary carcinoma is a rare and aggressive tumor and often seen in young adults with sickle cell hemoglobinopathies. Case presentation We report a case of renal medullary carcinoma in a 29-year old male patient with an occupying renal ...
Zhong-Ming Huang, Hai Wang, Zhi-Gang Ji
doaj   +1 more source

UNUSUAL PRESENTATION OF A THYROID MALIGNANCY: A CASE REPORT

National Journal of Medical Research, 2022
Medullary thyroid carcinoma is a rare malignancy. We report a case of Medullary thyroid carcinoma in a 56-year-old male patient. Patient presented with lower limb paresis and severe hypokalemia.
Lakshmi S Sunkara, Aparna Chinnam, Lakshmi kasa, Baleswari Golla   +3 more
doaj   +1 more source

Medullary thyroid carcinoma

Expert Review of Anticancer Therapy, 2023
Medullary thyroid carcinoma (MTC) constitutes approximately 5-10% of all thyroid cancers. Although the tumor forms in the thyroid, it doesn't originate from thyroid cells, but from the C cells or parafollicular cells which produce and release a hormone called calcitonin (CT). Starting from the second half of the 1900s, MTC was progressively studied and
Pelizzo, Maria Rosa, Mazza, Esmeralda Isabella, Mian, Caterina, Merante Boschin, Isabella   +3 more
openaire   +3 more sources

Risk Factors for Lateral Lymph Node Metastases in Patients With Sporadic Medullary Thyroid Carcinoma

Technology in Cancer Research & Treatment, 2020
Purpose: Medullary thyroid carcinoma is a rare endocrine malignancy; 75% of patients with this disease have sporadic medullary thyroid carcinoma. While surgery is the only curative treatment, the benefit of prophylactic lateral neck dissection is unclear.
Xin Wu MD, Binglu Li MD, Chaoji Zheng MD, Wei Liu MD, Tao Hong MD, Xiaodong He MD   +5 more
doaj   +1 more source