SUMMARY Calcitonin, a polypeptide hormone secreted by the parafollicular C cells of the thyroid gland, lowers serum calcium by decreasing bone resorption and tubular calcium reabsorption. An analgesic action, possibly mediated via β‐endorphins, is also evident.
C, Gennari, D, Agnusdei
openaire +2 more sources
Radioimmunoassay for calcitonin.
Calcitonin (CT) is one of the most recently discovered calcium-regulating hormones; the first brief allusion to its existence appeared in 1961.1 The first assays for CT were based on its hypocalcemic property upon injection into rats.2,3 Radioimmunoassays for animal calcitonins soon followed, but the availability of sensitive radioimmunoassays for ...
H, Heath, G W, Sizemore
openaire +2 more sources
Both injectable and nasal spray calcitonins have been utilized in the treatment of postmenopausal osteoporosis for over 25 years. More widespread use of calcitonin in the treatment of osteoporosis has been hampered in part due to poor patient acceptability and compliance and the inability of patients to take this medication as an oral pill.
Hamdy, Ronald C., Daley, Dane N.
openaire +7 more sources
Calcitonin and calcitonin receptors: bone and beyond
Calcitonin (CT), a 32 amino acid peptide hormone produced primarily by the thyroid, and its receptor (CTR) are well known for their ability to regulate osteoclast mediated bone resorption and enhance Ca2+ excretion by the kidney. However, recent studies now suggest that CT and CTRs may play an important role in a variety of processes as wide ranging as
openaire +3 more sources
Evaluation of the efficacy of salmon calcitonin nasal spray on bone healing following surgical removal of impacted third molar: a randomized controlled study. [PDF]
Nirmal H +6 more
europepmc +1 more source
The Pitfalls of Calcitonin as a Tumor Marker: Real-Life Data of Patients with Elevated Basal Calcitonin Levels but Without Evidence of Medullary Thyroid Carcinoma. [PDF]
Lederer AK +8 more
europepmc +1 more source
Covalent FAPI Imaging-Guided Precision Surgery in Patients with Medullary Thyroid Carcinoma: A Phase II Clinical Trial. [PDF]
Kong Z +17 more
europepmc +1 more source
Metastatic Medullary Thyroid Carcinoma Without Identifiable Primary Tumor Within the Thyroid Gland, Presenting with Initial Lymph Node Metastasis Followed by Distant Peritoneal Metastasis: A Case Report of a Rare Phenomenon. [PDF]
Lee E +6 more
europepmc +1 more source
Efficacy of coadministration of calcitonin and hyperbaric bupivacaine in spinal anesthesia for unilateral open inguinal hernia repair in tramadol abuse patients: a randomized controlled trial. [PDF]
Esmat IM +6 more
europepmc +1 more source

