Results 31 to 40 of about 99,464 (305)
The effects of calcitonin on quality of life in hypothyroid patients – A pilot study
Endocrine and Metabolic Science, 2023 Introduction: Hypothyroidism is a very common endocrine disorder routinely treated with levothyroxine replacement therapy. Despite treatment to biochemical euthyroidism, some individuals continue to have hypothyroidism-related symptoms.
Wedad Rahman +6 more
doaj +1 more source
N-Arachidonoyl Dopamine Modulates Acute Systemic Inflammation via Nonhematopoietic TRPV1. [PDF]
, 2017 N-Arachidonoyl dopamine (NADA) is an endogenous lipid that potently activates the transient receptor potential vanilloid 1 (TRPV1), which mediates pain and thermosensation. NADA is also an agonist of cannabinoid receptors 1 and 2.
Hellman, Judith +7 more
core +2 more sources
Armaghane Danesh Bimonthly Journal, 2022 Background & aim: Decreased bone density, especially in women, is a health risk factor; therefore, the aim of the present study was to investigate the effect of a resistance training course with vitamin D supplementation on bone absorption markers in ...
N Rouzbayani, M Fathi, M Rahmati
doaj
Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. [PDF]
PLoS ONE, 2012 INTRODUCTION: Treatment for osteoporosis commonly includes the use of bisphosphonates. Serious side effects of these drugs are caused by the inhibition of bone resorption as a result of osteoclast apoptosis.
Yi-Jie Kuo +9 more
doaj +1 more source
New players in the preventive treatment of migraine. [PDF]
, 2015 Migraine is a common, chronic disorder of the brain causing much disability, as well as personal, familial and societal impact. Several oral preventive agents are available in different countries for the prevention of migraine, but none have performed ...
Mitsikostas, Dimos D, Rapoport, Alan M
core +3 more sources
The Oncologist, EarlyView., 2021 Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth +10 more
wiley +1 more source
Tumour calcitonin. Interaction with specific calcitonin receptors [PDF]
Biochemical Journal, 1980 The human epidermoid bronchial carcinoma (BEN) cell line has been shown to have specific membrane binding sites for calcitonin and to secrete high-molecular-weight forms (ranging from 40000 to 10000) of immunoreactive calcitonin. Synthetic salmon and human calcitonins and a thyroid extract of porcine calcitonin have been shown to displace 125I-labelled
J, Ham, M L, Ellison, J, Lumsden
openaire +2 more sources
Frontiers in Veterinary ScienceObjectivesThis case-control study aimed to evaluate calcitonin response in naturally occurring hypercalcemia in cats and assess the relationships between calcitonin and ionized calcium (iCa) and examine relationships between calcitonin, iCa and bone ...
Evangelia Maniaki +4 more
doaj +1 more source
Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. [PDF]
, 2019 Denosumab has been used successfully to treat disease-associated osteoclast overactivity, including giant cell tumor of bone. Given its mechanism of action, denosumab is a potent potential treatment of other osteoclast bone dysplasias including central ...
Bernthal, Nicholas M +8 more
core +2 more sources
Receptor and secreted targets of Wnt-1/beta-catenin signalling in mouse mammary epithelial cells. [PDF]
, 2005 BackgroundDeregulation of the Wnt/ beta-catenin signal transduction pathway has been implicated in the pathogenesis of tumours in the mammary gland, colon and other tissues. Mutations in components of this pathway result in beta-catenin stabilization and
Ashworth, Alan +2 more
core +3 more sources